Prognostic Significance of <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.2723999pt" id="M1" height="15.8986pt" version="1.1" viewBox="-0.0657574 -15.6262 59.8529 15.8986" width="59.8529pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g121-78" d="M46 650V622C120 617 128 613 128 525V125C128 42 120 34 40 28V0H311V28C221 34 212 39 212 124V281L286 262C297 261 316 261 331 263C429 275 526 338 526 468C526 533 501 579 462 609C422 638 364 650 293 650H46ZM212 559C212 588 215 600 223 606C230 613 251 618 279 618C361 618 430 572 430 464C430 337 350 302 285 302C252 302 225 309 212 314V559Z"/></g><g transform="matrix(.017,0,0,-0.017,9.661,0)"><path id="g113-50" d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"/></g><g transform="matrix(.017,0,0,-0.017,17.898,0)"><path id="g113-55" d="M137 343C167 482 260 545 321 574C357 591 397 603 429 609L423 641C382 634 335 622 295 608C189 570 37 457 37 238C37 84 125 -12 242 -12C362 -12 447 89 447 209C447 311 374 393 267 393C247 393 226 386 204 376L137 343ZM227 337C318 337 361 256 361 173C361 105 336 22 258 22C176 22 126 120 126 240C126 266 127 291 132 310C155 323 189 337 227 337Z"/></g><g transform="matrix(.012,0,0,-0.012,26.197,-7.578)"><path id="g58-71" d="M308 0V33C225 38 217 44 217 128V521C217 605 225 612 308 617V650H39V617C122 612 130 605 130 521V128C130 44 122 38 39 33V0H308Z"/></g><g transform="matrix(.012,0,0,-0.012,30.377,-7.578)"><path id="g58-76" d="M731 650H485V618C556 614 580 601 585 558C588 530 592 485 592 390V153H589L173 650H22V618C69 614 92 606 112 582C131 558 132 555 132 483V266C132 175 129 128 125 96C120 49 95 36 36 33V0H281V33C212 36 188 50 183 98C180 129 177 175 177 266V510H179L603 -9H638V390C638 483 640 530 644 561C649 602 674 615 731 618V650Z"/></g><g transform="matrix(.012,0,0,-0.012,39.434,-7.578)"><path id="g58-73" d="M676 0V33C628 38 606 47 555 101S396 279 321 373C388 440 457 509 495 545C556 601 582 609 660 617V650H412V617L436 615C479 608 479 601 452 566C405 510 345 447 289 394C258 366 239 353 216 348V518C216 605 226 612 305 617V650H40V617C123 612 130 605 130 518V131C130 46 121 38 44 33V0H310V33C226 38 216 46 216 131V318C235 322 249 319 274 290C367 181 444 84 520 0H676Z"/></g><g transform="matrix(.012,0,0,-0.012,47.661,-7.578)"><path id="g50-53" d="M462 177V227H365V632H320C217 496 116 350 21 208V177H284V109C284 43 280 38 190 31V0H451V31C369 38 365 43 365 108V177H462ZM284 227H88C155 336 218 430 282 519H284V227Z"/></g><g transform="matrix(.012,0,0,-0.012,53.511,-7.578)"><path id="g58-95" d="M442 39L431 68C420 63 406 57 394 57C377 57 359 71 359 118V301C359 353 349 393 314 424C291 443 261 451 230 451C171 438 107 401 79 381C59 366 46 355 46 340C46 316 72 295 91 295C106 295 117 303 122 319C131 350 139 371 152 384C163 397 178 404 197 404C246 404 281 365 281 293V278C260 262 186 232 124 213C69 194 41 161 41 112C41 47 92 -12 163 -12C195 -12 243 25 283 51C288 35 293 22 308 7C319 -4 339 -12 354 -12L442 39ZM281 87C262 68 226 51 199 51C169 51 129 74 129 126C129 162 151 181 190 198C211 208 259 229 281 240V87Z"/></g></svg> Expression in Penile Squamous Cell Carcinoma: A Meta-Analysis with Trial Sequential Analysis

<div>Forest plot of the pooled outcome of five eligible studies on the association between <svg height="12.0444pt" id="M32" style="vertical-align:-0.2063999pt" version="1.1" viewbox="-0.0498162 -11.838 45.3431 12.0444" width="45.3431pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M46 650V622C120 617 128 613 128 525V125C128 42 120 34 40 28V0H311V28C221 34 212 39 212 124V281L286 262C297 261 316 261 331 263C429 275 526 338 526 468C526 533 501 579 462 609C422 638 364 650 293 650H46ZM212 559C212 588 215 600 223 606C230 613 251 618 279 618C361 618 430 572 430 464C430 337 350 302 285 302C252 302 225 309 212 314V559Z" id="g121-78"></path></g><g transform="matrix(.013,0,0,-0.013,7.319,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z" id="g113-50"></path></g><g transform="matrix(.013,0,0,-0.013,13.559,0)"><path d="M137 343C167 482 260 545 321 574C357 591 397 603 429 609L423 641C382 634 335 622 295 608C189 570 37 457 37 238C37 84 125 -12 242 -12C362 -12 447 89 447 209C447 311 374 393 267 393C247 393 226 386 204 376L137 343ZM227 337C318 337 361 256 361 173C361 105 336 22 258 22C176 22 126 120 126 240C126 266 127 291 132 310C155 323 189 337 227 337Z" id="g113-55"></path></g><g transform="matrix(.0091,0,0,-0.0091,19.846,-5.741)"><path d="M308 0V33C225 38 217 44 217 128V521C217 605 225 612 308 617V650H39V617C122 612 130 605 130 521V128C130 44 122 38 39 33V0H308Z" id="g58-71"></path></g><g transform="matrix(.0091,0,0,-0.0091,23.013,-5.741)"><path d="M731 650H485V618C556 614 580 601 585 558C588 530 592 485 592 390V153H589L173 650H22V618C69 614 92 606 112 582C131 558 132 555 132 483V266C132 175 129 128 125 96C120 49 95 36 36 33V0H281V33C212 36 188 50 183 98C180 129 177 175 177 266V510H179L603 -9H638V390C638 483 640 530 644 561C649 602 674 615 731 618V650Z" id="g58-76"></path></g><g transform="matrix(.0091,0,0,-0.0091,29.874,-5.741)"><path d="M676 0V33C628 38 606 47 555 101S396 279 321 373C388 440 457 509 495 545C556 601 582 609 660 617V650H412V617L436 615C479 608 479 601 452 566C405 510 345 447 289 394C258 366 239 353 216 348V518C216 605 226 612 305 617V650H40V617C123 612 130 605 130 518V131C130 46 121 38 44 33V0H310V33C226 38 216 46 216 131V318C235 322 249 319 274 290C367 181 444 84 520 0H676Z" id="g58-73"></path></g><g transform="matrix(.0091,0,0,-0.0091,36.107,-5.741)"><path d="M462 177V227H365V632H320C217 496 116 350 21 208V177H284V109C284 43 280 38 190 31V0H451V31C369 38 365 43 365 108V177H462ZM284 227H88C155 336 218 430 282 519H284V227Z" id="g50-53"></path></g><g transform="matrix(.0091,0,0,-0.0091,40.539,-5.741)"><path d="M442 39L431 68C420 63 406 57 394 57C377 57 359 71 359 118V301C359 353 349 393 314 424C291 443 261 451 230 451C171 438 107 401 79 381C59 366 46 355 46 340C46 316 72 295 91 295C106 295 117 303 122 319C131 350 139 371 152 384C163 397 178 404 197 404C246 404 281 365 281 293V278C260 262 186 232 124 213C69 194 41 161 41 112C41 47 92 -12 163 -12C195 -12 243 25 283 51C288 35 293 22 308 7C319 -4 339 -12 354 -12L442 39ZM281 87C262 68 226 51 199 51C169 51 129 74 129 126C129 162 151 181 190 198C211 208 259 229 281 240V87Z" id="g58-95"></path></g></svg> and penile cancer prognosis; HR, hazard ratio; CI, confidence interval.</div>

BioMed Research International

fig4

Figure 4

Figure 4: Prognostic Significance of <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.2723999pt" id="M1" height="15.8986pt" version="1.1" viewBox="-0.0657574 -15.6262 59.8529 15.8986" width="59.8529pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g121-78" d="M46 650V622C120 617 128 613 128 525V125C128 42 120 34 40 28V0H311V28C221 34 212 39 212 124V281L286 262C297 261 316 261 331 263C429 275 526 338 526 468C526 533 501 579 462 609C422 638 364 650 293 650H46ZM212 559C212 588 215 600 223 606C230 613 251 618 279 618C361 618 430 572 430 464C430 337 350 302 285 302C252 302 225 309 212 314V559Z"/></g><g transform="matrix(.017,0,0,-0.017,9.661,0)"><path id="g113-50" d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"/></g><g transform="matrix(.017,0,0,-0.017,17.898,0)"><path id="g113-55" d="M137 343C167 482 260 545 321 574C357 591 397 603 429 609L423 641C382 634 335 622 295 608C189 570 37 457 37 238C37 84 125 -12 242 -12C362 -12 447 89 447 209C447 311 374 393 267 393C247 393 226 386 204 376L137 343ZM227 337C318 337 361 256 361 173C361 105 336 22 258 22C176 22 126 120 126 240C126 266 127 291 132 310C155 323 189 337 227 337Z"/></g><g transform="matrix(.012,0,0,-0.012,26.197,-7.578)"><path id="g58-71" d="M308 0V33C225 38 217 44 217 128V521C217 605 225 612 308 617V650H39V617C122 612 130 605 130 521V128C130 44 122 38 39 33V0H308Z"/></g><g transform="matrix(.012,0,0,-0.012,30.377,-7.578)"><path id="g58-76" d="M731 650H485V618C556 614 580 601 585 558C588 530 592 485 592 390V153H589L173 650H22V618C69 614 92 606 112 582C131 558 132 555 132 483V266C132 175 129 128 125 96C120 49 95 36 36 33V0H281V33C212 36 188 50 183 98C180 129 177 175 177 266V510H179L603 -9H638V390C638 483 640 530 644 561C649 602 674 615 731 618V650Z"/></g><g transform="matrix(.012,0,0,-0.012,39.434,-7.578)"><path id="g58-73" d="M676 0V33C628 38 606 47 555 101S396 279 321 373C388 440 457 509 495 545C556 601 582 609 660 617V650H412V617L436 615C479 608 479 601 452 566C405 510 345 447 289 394C258 366 239 353 216 348V518C216 605 226 612 305 617V650H40V617C123 612 130 605 130 518V131C130 46 121 38 44 33V0H310V33C226 38 216 46 216 131V318C235 322 249 319 274 290C367 181 444 84 520 0H676Z"/></g><g transform="matrix(.012,0,0,-0.012,47.661,-7.578)"><path id="g50-53" d="M462 177V227H365V632H320C217 496 116 350 21 208V177H284V109C284 43 280 38 190 31V0H451V31C369 38 365 43 365 108V177H462ZM284 227H88C155 336 218 430 282 519H284V227Z"/></g><g transform="matrix(.012,0,0,-0.012,53.511,-7.578)"><path id="g58-95" d="M442 39L431 68C420 63 406 57 394 57C377 57 359 71 359 118V301C359 353 349 393 314 424C291 443 261 451 230 451C171 438 107 401 79 381C59 366 46 355 46 340C46 316 72 295 91 295C106 295 117 303 122 319C131 350 139 371 152 384C163 397 178 404 197 404C246 404 281 365 281 293V278C260 262 186 232 124 213C69 194 41 161 41 112C41 47 92 -12 163 -12C195 -12 243 25 283 51C288 35 293 22 308 7C319 -4 339 -12 354 -12L442 39ZM281 87C262 68 226 51 199 51C169 51 129 74 129 126C129 162 151 181 190 198C211 208 259 229 281 240V87Z"/></g></svg> Expression in Penile Squamous Cell Carcinoma: A Meta-Analysis with Trial Sequential Analysis 

BioMed Research International

Prognostic Significance of Expression in Penile Squamous Cell Carcinoma: A Meta-Analysis with Trial Sequential Analysis

Figure 4