Systematic Analysis of RNA Regulatory Network in Rat Brain after Ischemic Stroke

Figure 2

Aberrant expression of lncRNAs in rat brains after ischemic stroke. (a) Heatmap generated from the hierarchical cluster analysis shows the differential expressed genes (lncRNAs, miRNAs, and mRNAs) between ischemia and nonischemia rat brains. Green indicates downregulation and red indicates upregulation. (b) Real-time PCR validation of differential expressed lncRNAs in the ischemia and nonischemia rat brains. (c) Electrophoresis of 10 novel lncRNAs in the ischemia and nonischemia rat brains. (d) KEGG pathway analysis of differential expressed genes in the ischemia and nonischemia rat brains. (e) GO analysis of differential expressed genes in the ischemia and nonischemia rat brains.

(a)

(b)

(c)

(d)

(e)