Effect of Astragalus Polysaccharides on Cardiac Dysfunction in db/db Mice with Respect to Oxidant Stress

Figure 3

Effects of APS on myocardial cell apoptosis in db/db mice. Left ventricle was harvested from db/db mice with or without APS treatment (n=6 per group) after sacrifice. C57BJ/6J mice were taken as the normal control (n=6 per group). Sections of myocardium were subjected to the TUNEL assay for evaluation of apoptosis. (a)~(c) The microphotographs of TUNEL analysis in myocardium (brown stained nuclei: TUNEL staining positive, showing apoptosis; blue stained nuclei: TUNEL staining negative, showing normal). (d) The illustration for the percentage of apoptotic cardiomyocytes.

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