Research Article

Clinical and Etiological Aspects of Gynecomastia in Adult Males: A Multicenter Study

Table 1

Causes of gynecomastia in 237 patients (n = 244).

CausesN%TT (ng/mL)Prolactin (ng/mL)TSH (uIU/mL)LH (mIU/mL)FSH (mIU/mL)E2 (pg/mL)

Anabolic steroids3413.95.6 ± 1.313.7 ± 8.51.9 ± 0.84.0 ± 2.93.6 ± 1.930.3 ± 14.7
Hypogonadism2711.02.1 ± 1.113.9 ± 9.32.4 ± 0.619.2 ± 14.331.0 ± 23.229.9 ± 16.3
Pharmaceutical drugs197.84.8 ± 2.024.1 ± 34.11.9 ± 0.811.5 ± 12.517.1 ± 21.335.9 ± 14.7
Persistent puberty156.24.8 ± 2.013.7 ± 5.71.7 ± 1.04.8 ± 2.44.6 ± 4.330.1 ± 10.8
Hyperprolactinemia145.74.2 ± 1.9167.4 ± 335.92.8 ± 1.96.0 ± 6.212.0 ± 19.523.1 ± 9.7
Marijuana83.38.3 ± 2.79.8 ± 3.12.5 ± 1.64.9 ± 1.63.3 ± 2.144.0 ± 20.3
Renal Failure52.14.2 ± 2.316.7 ± 10.62.2 ± 1.48.9 ± 6.913.3 ± 14.924.2 ± 7.3
Hyperthyroidism52.15.7 ± 2.611.0 ± 6.70.02 ± 0.024.0 ± 2.03.7 ± 1.836.0 ± 19.0
Chronic liver disease31.24.5 ± 2.111.2 ± 4.41.9 ± 0.34.3 ± 0.65.6 ± 1.644.0 ± 30.8
Dietary phytosteroids10.47.68.50.862.41.248
Hyperestrogenism10.44.5202.53.64114
Refeeding10.412.710.44.74.10.958
Adrenal carcinoma10.42.478.1

Idiopathic11045.15.3 ± 1.812.3 ± 4.82.1 ± 1.24.3 ± 2.35.4 ± 5.628.4 ± 8.9