Case-Control Study and Meta-Analysis Show a Weak Association between ANTXR2 Polymorphisms and Ankylosing Spondylitis in Chinese Han

Table 2

Allele and genotype frequencies of ANTXR2 SNPs in Chinese Han AS⁺AAU^- patients, AS⁺AAU⁺ patients, and controls.

SNPs	Genotype	Control	AS^+AAU^-	P value	Pc	OR(95CI)	AS^+AAU^+	P value	Pc	OR(95CI)
rs6534639	CC	955	481	0.08	NS	0.88(0.72-1.05)	455	0.41	NS	1.03(0.86-1.22)
	CA	620	274	0.096	NS	1.13(0.95-1.35)	294	0.297	NS	1.06(0.88-1.27)
	AA	101	46	0.429	NS	1.05(0.74-1.51)	53	0.042	NS	0.70(0.48-1.03)
	A allele	822	366	0.104	NS	0.91(0.79-1.05)	400	0.191	NS	1.07(0.93-1.24)
rs4389526	AA	1469	751	0.055	NS	0.80(0.62-1.04)	698	0.1	NS	0.83(0.64-1.09)
	AT	210	87	0.069	NS	1.23(0.95-1.61)	84	0.119	NS	1.19(0.91-1.55)
	TT	7	2	0.379	NS	1.75(0.36-8.43)	2	0.417	NS	1.63(0.34-7.87)
	T allele	224	91	0.052	NS	0.81(0.61-1.04)	88	0.096	NS	0.84(0.65-1.08)
rs12504282	TT	1406	712	0.195	NS	1.11(0.89-1.37)	714	0.201	NS	0.90(0.72-1.13)
	TC	274	154	0.187	NS	0.90(0.71-1.12)	129	0.282	NS	1.09(0.86-1.35)
	CC	12	6	0.585	NS	1.03(0.39-2.76)	5	0.476	NS	1.20(0.42-3.43)
	C allele	298	166	0.214	NS	1.09(0.89-1.33)	139	0.25	NS	0.92(0.75-1.14)
rs10000471	CC	6	2	0.46	NS	1.53(0.31-7.57)	1	0.261	NS	3.03(0.36-25.17)
	CT	172	93	0.326	NS	0.93(0.71-1.22)	81	0.33	NS	1.08(0.82-1.42)
	TT	1496	755	0.437	NS	1.03(0.79-1.34)	760	0.267	NS	0.91(0.67-1.20)
	C allele	184	97	0.402	NS	0.96(0.75-1.24)	83	0.218	NS	1.12(0.86-1.46)