Research Article

Basic Fibroblast Growth Factor Fused with Tandem Collagen-Binding Domains from Clostridium histolyticum Collagenase ColG Increases Bone Formation

Figure 4

3D micro-CT images of femurs after injection of poly(Pro-Hyp-Gly)10 loaded with bFGF and CB-bFGFs. Three-dimensional images were created from 10 mm regions (500 slices) from the mid-femur using Tri-3D-Bon 3D image analysis software. 3D micro-CT images of fractured mouse femurs treated with (a) PBS, (b) bFGF, (c) bFGF-s3, (d) bFGF-s2b-s3, (e) bFGF-s3b, and (f) bFGF-s3a-s3b after four weeks of recovery. Red: callus; gray: existing bone. The scale bars indicate 3 mm.
(a)
(b)
(c)
(d)
(e)
(f)