Computational Approach to Investigating Key GO Terms and KEGG Pathways Associated with CNV

Table 1

Top 45 key GO terms associated with CNV.

GO term ID	GO term	GO description	MI value	Rank
GO: 0031091	Platelet alpha-granule	Cellular component	0.003	1
GO: 0031093	Platelet alpha-granule lumen	Cellular component	0.003	2
GO: 0060205	Cytoplasmic membrane-bounded vesicle lumen	Cellular component	0.003	3
GO: 0038133	ERBB2-ERBB3 signaling pathway	Biological process	0.003	4
GO: 0038129	ERBB3 signaling pathway	Biological process	0.003	5
GO: 1902847	Regulation of neuronal signal transduction	Biological process	0.003	6
GO: 0061517	Macrophage proliferation	Biological process	0.003	7
GO: 1902949	Positive regulation of tau protein kinase activity	Biological process	0.003	8
GO: 0061518	Microglial cell proliferation	Biological process	0.003	9
GO: 0031983	Vesicle lumen	Cellular component	0.003	10
GO: 0005576	Extracellular region	Cellular component	0.003	11
GO: 0035767	Endothelial cell chemotaxis	Biological process	0.003	12
GO: 0002580	Regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	Biological process	0.003	13
GO: 0044421	Extracellular region part	Cellular component	0.003	14
GO: 0007603	Phototransduction, visible light	Biological process	0.003	15
GO: 0001948	Glycoprotein binding	Molecular function	0.003	16
GO: 0072562	Blood microparticle	Cellular component	0.003	17
GO: 0044650	Adhesion of symbiont to host cell	Biological process	0.003	18
GO: 0019062	Virion attachment to host cell	Biological process	0.003	19
GO: 0010466	Negative regulation of peptidase activity	Biological process	0.003	20
GO: 0009584	Detection of visible light	Biological process	0.003	21
GO: 0010951	Negative regulation of endopeptidase activity	Biological process	0.003	22
GO: 0001654	Eye development	Biological process	0.003	23
GO: 0002581	Negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	Biological process	0.003	24
GO: 0052547	Regulation of peptidase activity	Biological process	0.003	25
GO: 0052548	Regulation of endopeptidase activity	Biological process	0.003	26
GO: 0005791	Rough endoplasmic reticulum	Cellular component	0.003	27
GO: 0050839	Cell adhesion molecule binding	Molecular function	0.003	28
GO: 0071307	Cellular response to vitamin K	Biological process	0.003	29
GO: 1902430	Negative regulation of beta-amyloid formation	Biological process	0.003	30
GO: 0005604	Basement membrane	Cellular component	0.003	31
GO: 0030023	Extracellular matrix constituent conferring elasticity	Molecular function	0.003	32
GO: 2000768	Positive regulation of nephron tubule epithelial cell differentiation	Biological process	0.003	33
GO: 1903002	Positive regulation of lipid transport across blood brain barrier	Biological process	0.003	34
GO: 1903000	Regulation of lipid transport across blood brain barrier	Biological process	0.003	35
GO: 1903001	Negative regulation of lipid transport across blood brain barrier	Biological process	0.003	36
GO: 1902951	Negative regulation of dendritic spine maintenance	Biological process	0.003	37
GO: 1902999	Negative regulation of phospholipid efflux	Biological process	0.003	38
GO: 1901627	Negative regulation of postsynaptic membrane organization	Biological process	0.003	39
GO: 2001139	Negative regulation of phospholipid transport	Biological process	0.003	40
GO: 0046911	Metal chelating activity	Molecular function	0.003	41
GO: 0030574	Collagen catabolic process	Biological process	0.003	42
GO: 0007423	Sensory organ development	Biological process	0.003	43
GO: 0001968	Fibronectin binding	Molecular function	0.003	44
GO: 0051346	Negative regulation of hydrolase activity	Biological process	0.003	45