Blood Biochemical and Hematological Study after Subacute Intravenous Injection of Gold and Silver Nanoparticles and Coadministered Gold and Silver Nanoparticles of Similar Sizes
Table 2
Relative organ weights of male rats in after 4 weeks of AgNP, AuNP, and AgNP/AuNP mix administration (n-5).
Dose (μg/kg)
G1
G2
G3
G4
G5
G6
G7
Control
Silver 10
Silver 100
Gold 10
Gold 100
Mix 10
Mix 100
BODY WEIGHT (g)
368.11±8.25
356.88±8.49
378.02±18.05
374.50±13.78
400.18±13.50
378.19±6.87
381.78±14.58
TESTIS (LEFT)
0.48±0.004
0.46±0.03
0.45±0.03
0.43±0.02
0.45±0.01
0.44±0.02
0.47±0.02
TESTIS (RIGHT)
0.48±0.01
0.46±0.03
0.45±0.03
0.43±0.02
0.44±0.01
0.44±0.02
0.47±0.02
KIDNEY (LEFT)
0.37±0.02
0.37±0.02
0.37±0.01
0.36±0.01
0.37±0.01
0.38±0.02
0.36±0.01
KIDNEY (RIGHT)
0.37±0.02
0.38±0.02
0.37±0,01
0.37±0.01
0.36±001
0.36±0.01
0.37±0.003
SPLEEN
0.24±0.04
0.19±0.01
0.20±0.01
0.20±0.01
0.27±0.02
0.21±0.01
0.21±0.01
LIVER
2.99±0.05
2.79±0.08
2.90±0.12
2.78±0.08
2.97±0.04
2.75±0.09
2.71±0.03
THYMUS
0.12±0.01
0.10±0.004
0.10±0.01
0.12±0.01
0.13±0.02
0.14±0.01
0.11±0.01
HEART
0.33±0.02
0.36±0,01
0.33±0.01
0.34±0.01
0.33±0.01
0.34±0.02
0.33±0.01
LUNG (LEFT)
0.12±0,005
0.13±0.01
0.12±0.004
0.13±0.01
0.13±0.002
0.13±0.004
0.13±0.002
LUNG (RIGHT)
0.22±0.01
0.24±0.02
0.23±0.01
0.25±0.01
0.25±0.01
0.25±0.01
0.24±0.004
BRAIN
0.54±0.01
0.57±0.02
0.53±0.03
0.55±0.02
0.53±0.02
0.53±0.01
0.53±0.02
, p<0.05, comparing with control group; relative organ weight = organ weight/body weight x 100.