Blood Biochemical and Hematological Study after Subacute Intravenous Injection of Gold and Silver Nanoparticles and Coadministered Gold and Silver Nanoparticles of Similar Sizes
Table 8
Blood coagulation test of male rats in injection and recovery group.
Group
APTT (mean±S.E)
PT (mean±S.E)
Control Injection (5)
14.96 ± 1.29
14.12 ± 0.58
Control Recovery (3)
17.47 ± 1.28
15.43 ± 0.94
AgNP 10 μg/kg Injection (5)
16.14 ± 0.77
14.44 ±0.29
AgNP 10 μg/kg Recovery (3)
16.40 ± 0.55
15.47 ± 1.03
AgNP 100 μg/kg Injection (5)
15.64 ± 0.67
14.26 ± 0.47
AgNP 100 μg/kg Recovery (3)
17.50 ± 0.20
15.90 ± 0.40
AuNP 10 μg/kg Injection (5)
14.14 ± 0.67
14.12 ± 0.49
AuNP 10 μg/kg (3) Recovery
16.93 ± 0.29
15.70 ± 0.21
AuNP 100 μg/kg Injection (5)
16.88 ± 1.14
15.20 ± 0.35
AuNP 100 μg/kg Recovery (3)
14.90 ± 0.95
14.80 ± 0.67
AgNP/AuNP Mix Injection 10/10 μg/kg (5)
16.40 ± 0.50
16.06 ± 0.45
AgNP/AuNP Mix recovery 10/10 μg/kg (3)
16,57 ± 0.85
16.23 ± 0.17
AgNP/AuNP Mix Injection 100/100 μg/kg (5)
18.04 ± 1.76
14.70 ± 0.63
AgNP/AuNP Mix Recovery 100/100 μg/kg (3)
17.30 ± 1.22
17.30 ± 1.12
( ): number of animals. : activated partial thromboplastin time (sec). : prothrombin time (sec).
