Siji Antiviral Mixture Protects against CA16 Induced Brain Injury through Inhibiting PERK/STAT3/NF-κB Pathway

<div>Effect of SAM on CA16 induced ER stress and inflammatory response in SH-SY5Y cell. (a) After different treatment, total proteins were extracted. CHOP, GRP78, PERK, P-PERK, OASIS P- elF2α, and elF2α expression levels were detected by Western blotting with the corresponding antibodies. (b) CA16 induced expression of NF-κB and phosphorylation of STAT3, and SAM treatment significantly decreased this effect. ##P&lt;0.01 versus control group; ∗P&lt;0.05; ∗∗P&lt;0.01 versus model group.</div>

BioMed Research International

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Figure 7

Figure 7: Siji Antiviral Mixture Protects against CA16 Induced Brain Injury through Inhibiting PERK/STAT3/NF-κB Pathway