High Incidence of Gastrointestinal Ulceration and Cytogenetic Aberration of Trisomy 8 as Typical Features of Behçet’s Disease Associated with Myelodysplastic Syndrome: A Series of 16 Consecutive Chinese Patients from the Shanghai Behçet’s Disease Database and Comparison with the Literature

Table 1

Clinical characteristics of patients with BD and/without MDS.

	BD with MDS; ()	BD without MDS; ()
Age at BD diagnosis (y), mean (SD)	49.9 ± 12.4	37.9 ± 12.8	0.00
Age at MDS diagnosis (y), mean (SD)	47.5 ± 12.2	-	-
Male (%)	4 (25.0)	409 (51.8)	0.04
Oral ulcer	16 (100)	777 (98.5)	0.821
Genital ulcer	14 (87.5)	558 (70.7)	0.432
Ocular lesion	0 (0)	102 (12.9)	0.391
Arthritis	5 (31.3)	178 (22.6)	0.714
Skin lesions	7 (43.8)	510 (64.6)	0.084
Positive pathergy test	3 (18.8)	55 /125 (44.0)	0.062
Central nervous system	0 (0)	14 (1.8)	>0.99
Vascular lesions	0 (0)	31 (3.9)	>0.99
GI involvement	10 (62.5)	94 (11.9)	<0.00
Fever	9 (56.3)	7 (1.9)	<0.00
Laboratory findings at diagnosis of BD
CRP (mg/L)	54.8 ± 40.8	12.74 ± 22.16	0.00
ESR (mm/h)	80.2 ± 29.7	23.74 ± 24.38	<0.00
WBC (10^9/L)	3.6 ± 2.2	7.2 ± 2.5	<0.00
Hemoglobin (g/L)	88.8 ± 18.7	135.6 ± 19.4	<0.00
Platelets (10^9/L)	144.0 ± 109.0	228.5 ± 75.9	0.01

. BD: Behçet disease; GI: gastrointestinal; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; WBC: white blood cells.