High Incidence of Gastrointestinal Ulceration and Cytogenetic Aberration of Trisomy 8 as Typical Features of Behçet’s Disease Associated with Myelodysplastic Syndrome: A Series of 16 Consecutive Chinese Patients from the Shanghai Behçet’s Disease Database and Comparison with the Literature

Table 3

Symptoms and laboratory findings in patients with intestinal BD according to trisomy 8.

	Intestinal BD with trisomy 8 ()	Intestinal BD without trisomy 8 ()
Age at diagnosis of intestinal BD (years)	49.5 ± 12.8	30.7 ± 12.9	0.00
Male (%)	2 (20.0)	5 (50.0)	0.348
Duration (months)	158 ± 50	40 ± 13	0.058
Systemic signs
Oral ulcer	10 (100)	10 (100)	-
Genital ulcer	8 (80.0)	7 (70.0)	>0.99
Ocular lesion	0 (0)	0 (0)	-
Arthralgia	3 (30.0)	3 (30.0)	>0.99
Skin lesions	4 (40.0)	3 (30.0)	>0.99
Positive pathergy test	3 (30.0)	2 (20.0)	>0.99
Central nerve system	0 (0)	0 (0)	-
Symptoms of GI involvement
Abdominal pain	7 (70.0)	8 (80.0)	>0.99
Melena/hematochezia	4 (40.0)	5 (50.0)	>0.99
Diarrhea	5 (50.0)	6 (60.0)	>0.99
Weight loss	8 (80.0)	5 (50.0)	>0.99
Fever	6 (60.0)	1 (10.0)	>0.99
Perforation	0 (0)	3 (30.0)	>0.99
Ileus	1 (10.0)	3 (30.0)	>0.99
Location of intestinal ulcers
Esophagus	0 (0)	1 (10.0)	>0.99
Ileocecal	9 (90.0)	6 (60.0)	0.302
Small intestine	1 (10.0)	2 (20.0)	0.323
Colon	1 (10.0)	2 (20.0)	>0.99
Laboratory findings at BD diagnosis
CRP (mg/L)	63.3 ± 41.4	44.5 ± 51.5	0.381
ESR (mm/h)	91.9 ± 21.5	39.2 ± 27.4	<0.00
WBC (10^9/L)	3.7 ± 2.5	8.5 ± 4.0	0.00
Hemoglobin (g/L)	89.7 ± 17.7	111.6 ± 15.3	0.00
Platelets (10^9/L)	163.9 ± 116.4	339.1 ± 136.6	0.00

. BD: Behçet disease; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; WBC: white blood cell.