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Author
(Year) | Country | Treatment and comparison | Equipment | Patients | Lesions examined | Mean age | % Male | Population | Endoscopists | Blinded pathologist | Study design |
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| Dobashi et al. (2016) [24] | Japan | ME-NBI (Simplified criteria) | GIF-H260Z; Olympus, 19-in high- resolution liquid-crystal monitor (OEV191H; Olympus) | 147 | 54 | 67 | 88% | ESCC | 2 | Yes | Post hoc analysis |
| Goda. et al. (2015) [14] | Japan | LCE-PS (Lugol chromoendoscopy with pink-color sign) VS ME-NBI | GIF-H260Z; Olympus, 19-in high- resolution liquid-crystal (OEV191H; Olympus) | 147 | 305 | 67 | 88% | SESCC | 2 | Yes | RCT (cross-sectional) |
| Lee et al. (2010) [10] | China | ME-NBI vs. conventional endoscopy | GIF-Q240Z or GIF-FQ260Z; Olympus | 69 | 45 | 54 | 98.60% | HNC | 4 | Yes | RCT (crossover) |
| Nagai et al. (2014) [25] | Japan | ME-NBI vs. histologic diagnosis | GIF-H260Z; Olympus, 19-inch high-resolution liquid-crystal monitor (OEV19H, Olympus) | 85 | 111 | / | / | ESCC | / | Yes | RCT (crossover) |
| Ishihara et al. (2010) [26] | Japan | Experienced endoscopists vs. less experienced endoscopists | GIF-H260Z, Olympus | 350 | 162 VS 186 | 66 | 82% | History of ESCC or/and HNC | 5 | Yes | RCT (cross-sectional) |
| Asada-Hirayama et al. (2013) [27] | Japan | ME-NBI vs. lugol chromoendoscopy | GIF-Q240Z or GIF-FQ260Z; Olympus | 28 | 72 | 69 | 89% | ESCC or HGIN | / | Yes | Retrospective study |
|
| Invasion depth staging studies | |
| Goda. et al. (2009) [28] | Japan | N-HRE vs. ME-NBI vs. HF-EUS | GIF-2T240; Olympus; UM-3R; Olympus | 72 | 101 | 65 | 86% | SESCC | 3 | Yes | RCT (cross-sectional) |
| Ebi et al. (2015) [29] | USA
Japan | WLI vs. WLI + ME-NBI | GIF-Q260Z; Olympus | 49 | 55 | 68 | 83.70% | SESCC | 11 | Yes | RCT (crossover) (multicenter, prospective) |
| Lee et al. (2014) [30] | Korea | ME-NBI vs. HF-EUS | GIF-H260Z; Olympus; GIF-2T240, Olympus; UM3D-DP20-25R, Olympus | 45 | 46 | 66 | 93.30% | ESCC | 1 | Yes | Retrospective study |
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