Association between a Genetic Risk Score Based on Single Nucleotide Polymorphisms of Coronary Artery Disease-Related Genes and Left Main Coronary Artery Disease
Table 1
Baseline characteristics of patients.
LMCAD (n=488)
MPCAD (n=1056)
p value
Age (yr)
62.28 (±8.47)
60.88 (±8.68)
0.003
Male Sex
407 (83.4)
830 (78.6)
0.028
BMI (kg/m2)
25.51 (±3.15)
25.87 (±5.51)
0.183
Smoking
248 (50.8)
536 (50.8)
0.982
Hypertension
320 (65.6)
706 (66.9)
0.620
Hyperlipidemia
329 (67.4)
713 (67.5)
0.969
Diabetes mellitus
154 (31.6)
360 (34.1)
0.326
Chronic renal dysfunction
2 (0.4)
9 (0.9)
0.519
COPD
2 (0.4)
5 (0.5)
1.000
Peripheral vascular disease
15 (3.1)
19 (1.8)
0.113
Prior MI
162 (33.2)
424 (40.2)
0.009
Prior PCI
48 (9.8)
102 (9.7)
0.913
EF (%)
60.20 (±8.07)
59.38 (±8.87)
0.071
Values are mean (±SD) or n (%). LMCAD indicates left main coronary artery disease; MPCAD: more peripheral coronary artery disease; BMI: body mass index; COPD: chronic obstructive pulmonary disease; MI: myocardial infarction; PCI: percutaneous coronary intervention; EF: ejection fraction.
