Neural Plastic Changes in the Subcortical Auditory Neural Pathway after Single-Sided Deafness in Adult Mice: A MEMRI Study

Figure 1

Schematic diagram of the present study. B57BL/6 mice (postnatal 8-week) were divided into three groups: (1) normal-hearing control group (n = 9, postnatal 8-week), (2) the single-sided deafness- (SSD-) 4-week group (n = 11, postnatal 12-week), and (3) the SSD-8-week group (n = 11, postnatal 16-week). After intraperitoneal injection of 90 mg/kg MnCl₂ solution, all mice were exposed to white Gaussian noise for 24 hours. Then, MRI was acquired (ip: intraperitoneal injection).