Zerumbone-Loaded Nanostructured Lipid Carrier Induces Apoptosis of Canine Mammary Adenocarcinoma Cells

Figure 8

Toxicity of ZER-NLC, ZER, and doxorubicin on canine mammary gland tumor (CMT) adenocarcinoma cells. (a) Lethal concentration (LC₅₀), (b) total growth inhibition concentration (TGI), and (c) growth inhibition concentration 50 (GI₅₀) of ZER-NLC, ZER, and DOXO at 24, 48, and 72 h of incubation. For each incubation period, means with different roman numerals were significantly different (p<0.05) from each other. DOXO: doxorubicin; ZER: zerumbone; ZER-NLC: zerumbone-loaded nanostructured lipid carrier.

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