Zerumbone-Loaded Nanostructured Lipid Carrier Induces Apoptosis of Canine Mammary Adenocarcinoma Cells

Table 4

Molecular markers for murine (3T3) fibroblast and canine mammary gland tumor (CMT) adenocarcinoma cells.

Genes	Gene Expression
	3T3 Murine fibroblast	Canine mammary gland adenocarcinoma cell
CK-8	-	+
HPRT	+	+
ER	-	-
PGR	-	+
VEGF	-	+
HER-2	-	+
HIF-1α	-	+
Bcl-2	-	+
MMP-2	-	+
EPOR	-	+

-: negative; +: positive; CK-8: cytokeratin-8; HPRT: hypoxanthine ribosyltransferase; ER: estrogen receptor; PGR: progesterone receptor; VEGF: vascular endothelial growth factor; HER-2: human epidermal growth factor receptor-2; HIF-1α: hypoxia-inducing factor-1α; Bcl-2: B-cell lymphoma-2; MMP-2: matrix metalloproteinases-2; EPOR: erythropoietin receptor.