Relationship of Red Blood Cell Distribution Width with Cancer Mortality in Hospital
Table 1
Baseline characteristics of the study population.
Characteristics
RDW ()
P-value
11.5-14.3
14.4-16.3
16.4-30.5
RDW start
13.5 ± 0.6
15.2 ± 0.6
18.2 ± 1.6
<0.001
Clinical parameters, n (%)
1117
1112
1155
Age, years
64.7 ± 14.9
68.2 ± 13.9
67.0 ± 14.3
<0.001
Gender, n (%)
0.533
Male
487 (43.6)
493 (44.3)
530 (45.9)
Female
630 (56.4)
619 (55.7)
625 (54.1)
Ethnicity, n (%)
0.015
White
812 (72.7)
838 (75.4)
840 (72.7)
Black
72 (6.4)
76 (6.8)
109 (9.4)
Other
233 (20.9)
198 (17.8)
206 (17.8)
SBP, mmHg
119.3 ± 15.5
118.1 ± 16.7
115.2 ± 16.6
<0.001
DBP, mmHg
61.8 ± 9.7
60.5 ± 10.3
59.8 ± 10.5
<0.001
Heart rate, beats/minute
87.7 ± 16.1
90.1 ± 16.2
92.1 ± 17.4
<0.001
Respiratory rate, beats/minute
18.9 ± 4.3
19.7 ± 4.5
20.0 ± 4.4
<0.001
Comorbidities
Atrial fibrillation, n (%)
273 (24.4)
324 (29.1)
342 (29.6)
0.010
Congestive heart failure, n (%)
92 (8.2)
156 (14.0)
160 (13.9)
<0.001
Renal disease, n (%)
63 (5.6)
128 (11.5)
158 (13.7)
<0.001
Liver disease, n (%)
37 (3.3)
80 (7.2)
95 (8.2)
<0.001
Valvular disease, n (%)
380 (34.0)
415 (37.3)
462 (40.0)
0.013
Stroke, n (%)
112 (10.0)
93 (8.4)
77 (6.7)
0.015
Pneumonia, n (%)
307 (27.5)
357 (32.1)
358 (31.0)
0.046
Laboratory parameters
Body mass index, kg/m2
27.3 ± 5.8
27.7 ± 6.3
27.6 ± 5.7
0.524
White blood cell count, 10 9 /L
12.5 ± 6.7
13.1 ± 11.0
15.1 ± 26.9
<0.001
Platelet count, 10 9 /L
246.7 ± 121.5
239.6 ± 149.0
224.1 ± 171.1
0.001
BUN, mg/dl
20.9 ± 15.6
27.6 ± 22.5
31.8 ± 25.0
<0.001
Serum potassium, mmol/L
4.2 ± 0.5
4.2 ± 0.6
4.2 ± 0.6
0.028
Hemoglobin, g/dl
11.4 ± 1.8
10.5 ± 1.7
9.8 ± 1.6
<0.001
Hematocrit, %
33.6 ± 5.3
31.2 ± 5.1
29.6 ± 4.9
<0.001
Serum anion gap, mmol/L
13.9 ± 3.0
14.3 ± 3.8
14.9 ± 3.9
<0.001
Serum bicarbonate, mmol/L
23.9 ± 3.9
23.5 ± 4.5
22.9 ± 4.6
<0.001
Serum creatinine, mg/dl
1.1 ± 0.8
1.4 ± 1.6
1.4 ± 1.3
<0.001
Serum glucose, mg/dl
148.3 ± 52.9
144.6 ± 47.4
141.0 ± 55.4
0.004
Scoring systems
SOFA
3.8 ± 2.8
4.7 ± 3.1
5.5 ± 3.5
<0.001
Hospital expire
145 (13.0)
222 (20.0)
321 (27.8)
<0.001
Renal replace therapy
34 (3.0)
49 (4.4)
80 (6.9)
<0.001
BUN: blood urea nitrogen, SBP: systolic blood pressure, DBP: diastolic blood pressure, and SOFA: sequential organ failure assessment. Normally distributed data are presented as the mean (SD) (analysis of variance); nonnormally distributed data are presented as median (IQR) (nonparametric Wilcoxon test); and categorical variables are presented as n (%) (Chi-square test).
