Increased Risk for Hip Fractures among Patients with Cholangitis: A Nationwide Population-Based Study

Table 3

Incidence and adjusted hazard ratio of hip fracture stratified by sex, age, and comorbidities between the two cohorts.

Variables	Cholangitis						Compared to noncholangitis cohort
		No			Yes
	Event	PY	Rate	Event	PY	Rate	Crude HR (95% CI)	Adjusted HR^†(95% CI)
Overall	366	62466	5.86	101	13332	7.58	1.29 (1.03-1.61)	1.29 (1.03-1.61)
Sex
Women	218	30211	7.22	61	6619	9.22	1.27 (0.96-1.69)	1.27 (0.96-1.70)
Men	148	32255	4.59	40	6713	5.96	1.29 (0.91-1.83)	1.27 (0.89-1.82)
Age, year
<65	19	32802	0.58	15	7298	2.06	3.53 (1.80-6.96)	2.65 (1.30-5.39)
≥65	347	29664	11.7	86	6034	14.3	1.22 (0.96-1.54)	1.15 (0.90-1.45)
Comorbidity
No	29	21929	1.32	9	3348	2.69	2.04 (0.97-4.31)	3.01 (1.42-6.41)
Yes	337	40536	8.31	92	9984	9.21	1.11 (0.88-1.39)	1.26 (1.00-1.59)

PY, person-year; rate, incidence density (per 1,000 person-years); HR, hazard ratio; adjusted HR^†: multiple analysis including age, sex, each comorbidity, and oral steroid used; CI: confidence interval