Clinical Study

Eradication of HCV in Renal Transplant Recipients and Its Effects on Quality of Life

Table 1

Patient characteristics at baseline (n=16).

Demographic characteristics

 Age, y64 (26-71)
 Sex (M/F)11/5
 Time from RTX to HCV therapy, mo150.9 (84.4)

Cause of end-stage renal disease

  Vesicoureteral reflux1
 Chronic glomerulonephritis6
 Others or unknown9

HCV genotype:

 1a1
 1b10
 24
 41

Baseline laboratory values

 Creatinine, mg/dL1.29 (0.80-1.80)
 eGFR, mL/min/1.73 m260.3 (19.3)
 Proteinuria (g/24 hours)0.582 (0,768)
 Bilirubin: total, mg/dL0.58 (0.50-0.80)
 GGT, U/L47.5 (16-306)
 ALT, U/L30.2 (11 -137)
 AST, U/L31.4 (17 -85)
 ALP, U/L95.1 (41.3)
 Total serum protein, g/dL6.91 (0.50)
 Albumin, g/dL4.15 (0.37)
 AFP, IU/mL2.93 (2.62)
 Hemoglobin, g/dL12.87 (1.13)
 WBC count, /μL7.40 (1.57)
 Platelet count, /μL218.43 (62.16)
 FibroScan value (kPa)9.31 (1.75)
 Viral load (log10 IU/mL)2.1E (4.1E-1.3E)

Data are expressed as median (range) or mean (standard deviation). Abbreviations. eGFR: estimated glomerular filtration rate; GGT: γ-glutamyl-transpeptidase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; AFP: alpha fetoprotein (0-4 IU/ml).