Clinical Study
Eradication of HCV in Renal Transplant Recipients and Its Effects on Quality of Life
Table 1
Patient characteristics at baseline (n=16).
| Demographic characteristics |
| Age, y | 64 (26-71) | Sex (M/F) | 11/5 | Time from RTX to HCV therapy, mo | 150.9 (84.4) |
| Cause of end-stage renal disease |
| Vesicoureteral reflux | 1 | Chronic glomerulonephritis | 6 | Others or unknown | 9 |
| HCV genotype: |
| 1a | 1 | 1b | 10 | 2 | 4 | 4 | 1 |
| Baseline laboratory values |
| Creatinine, mg/dL | 1.29 (0.80-1.80) | eGFR, mL/min/1.73 m2 | 60.3 (19.3) | Proteinuria (g/24 hours) | 0.582 (0,768) | Bilirubin: total, mg/dL | 0.58 (0.50-0.80) | GGT, U/L | 47.5 (16-306) | ALT, U/L | 30.2 (11 -137) | AST, U/L | 31.4 (17 -85) | ALP, U/L | 95.1 (41.3) | Total serum protein, g/dL | 6.91 (0.50) | Albumin, g/dL | 4.15 (0.37) | AFP, IU/mL | 2.93 (2.62) | Hemoglobin, g/dL | 12.87 (1.13) | WBC count, /μL | 7.40 (1.57) | Platelet count, /μL | 218.43 (62.16) | FibroScan value (kPa) | 9.31 (1.75) | Viral load (log10 IU/mL) | 2.1E (4.1E-1.3E) |
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Data are expressed as median (range) or mean (standard deviation) . Abbreviations. eGFR: estimated glomerular filtration rate; GGT: γ-glutamyl-transpeptidase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; AFP: alpha fetoprotein (0-4 IU/ml). |