Research Article
Uncontrolled Diabetes Mellitus Has No Major Influence on the Platelet Transcriptome
Table 1
Baseline characteristics of the patients. BMI: body mass index and ASA: acetylsalicylic acid.
| | | Diabetes | no Diabetes | p value |
| | Male sex | 3 (60%) | 3 (60%) | 1 | | Age (years) | 70 63-72 | 63 59-70 | 0.492 | | BMI (kg/m2) | 33.4 32.0-35.3 | 31.8 30.5-38.8 | 0.841 | | Hypertension | 5 (100%) | 4 (80%) | 1 | | Active smoking | 1 (20%) | 1 (20%) | 1 | | Coronary artery disease | 4 (80%) | 2 (40%) | 0.524 | | Remote coronary intervention | 3 (60%) | 2 (40%) | 1 | | Reduced left ventricular function | 2 (40%) | 2 (40%) | 1 | | Medication | | | | | Insulin | 3 (60%) | 0 (0%) | 0.167 | | Oral antidiabetics | 3 (60%) | 0 (0%) | 0.167 | | ASA | 3 (60%) | 3 (60%) | 1 | | Oral anticoagulation | 3 (60%) | 2 (40%) | 1 | | Statins | 3 (60%) | 2 (40%) | 1 | | Laboratory parameters | | | | | Platelets (103/μl) | 236 183-238 | 212 207-225 | 1 | | Leukocytes (103/μl) | 9.0 6.3-9.2 | 8.6 6.2-9.0 | 0.548 | | Hemoglobin (g/dl) | 13.4 12.6-13.8 | 14.7 14.3-14.8 | 0.143 | | Total cholesterol (mg/dl) | 163 160-168 | 178 168-219 | 0.111 | | LDL cholesterol (mg/dl) | 104 65-106 | 126 114-128 | 0.056 | | HDL cholesterol (mg/dl) | 38 29-41 | 49 42-87 | 0.111 | | Triglycerides (mg/dl) | 203 100-280 | 150 118-151 | 0.690 | | Serum glucose (mg/dl) | 255 202-256 | 97 87-107 | 0.151 | | HbA1c (%) | 9.0 8.5-9.9 | 5.5 5.4-5.7 | 0.008 | | C-reactive protein (mg/dl) | 0.8 0.6-1.2 | 0.3 0.1-0.3 | 0.048 | | Creatinine (mg/dl) | 1.0 0.9-1.5 | 0.9 0.8-1.0 | 0.444 |
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