Research Article

Mutational Profiling of Non-Small-Cell Lung Cancer Resistant to Osimertinib Using Next-Generation Sequencing in Chinese Patients

Table 1

Patients’ characteristics.

#SexAge (yrs)EGFR typeTissues and genetic testing
Before osimertinibAfter osimertinib

1F62L858RLungNGSPleuraNGS
2M8519 delSLARMs-PCRLungNGS
3M6619 delBoneARMs-PCRLungNGS
4F79L858RLungARMs-PCRLungNGS
5F8919 delLungNGSLungNGS
6F6619 delSerumARMs-PCRBoneNGS
7M5619 delLungARMs-PCRLungNGS
8F7519 delPleuraARMs-PCRPleuraNGS
9M5119 delLungARMs-PCRLungNGS
Median66

SL denotes supraclavicular lymph node.