Research Article
Mutational Profiling of Non-Small-Cell Lung Cancer Resistant to Osimertinib Using Next-Generation Sequencing in Chinese Patients
Table 1
Patients’ characteristics.
| # | Sex | Age (yrs) | EGFR type | Tissues and genetic testing | Before osimertinib | After osimertinib |
| 1 | F | 62 | L858R | Lung | NGS | Pleura | NGS | 2 | M | 85 | 19 del | SL | ARMs-PCR | Lung | NGS | 3 | M | 66 | 19 del | Bone | ARMs-PCR | Lung | NGS | 4 | F | 79 | L858R | Lung | ARMs-PCR | Lung | NGS | 5 | F | 89 | 19 del | Lung | NGS | Lung | NGS | 6 | F | 66 | 19 del | Serum | ARMs-PCR | Bone | NGS | 7 | M | 56 | 19 del | Lung | ARMs-PCR | Lung | NGS | 8 | F | 75 | 19 del | Pleura | ARMs-PCR | Pleura | NGS | 9 | M | 51 | 19 del | Lung | ARMs-PCR | Lung | NGS | Median | | 66 | | | | | |
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SL denotes supraclavicular lymph node.
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