Investigation of MicroRNA in Mitochondrial Apoptotic Pathway in Systemic Lupus Erythematosus

Table 1

Demographic clinical data of SLE patients and healthy controls.

	Normal controls	SLE	value
	()	()
Age (year)			0.07
Leukocytes (×1000/ml)			0.11
Hemoglobin (mg/dL)			0.12
Hematocrit (%)			0.05
c-reactive protein (mg/dL)			0.23
Aspartate aminotransferase (U/dL)			0.42
Alanine aminotransferase (U/dL)			0.39
Total cholesterol (mg/dL)			<0.05
high-density lipoprotein (mg/dL)			0.31
low-density lipoprotein (mg/dL)			0.94
Triglyceride (mg/dL)			0.04
Creatinine (mg/dL)			0.37
Gender (female: male)	21:08	11:02	0.47
Use of statins (yes: no)	03:26	01:12	0.64
plasma microRNA: miR-541a as control (CT)
miR-22-3p ΔCT			0.79
miR-150-5p ΔCT			<0.01
miR-221-3p ΔCT			0.01
miR-21-5p ΔCT			<0.01

SLE, systemic lupus erythematosus; §, data presented with mean ± SD (standard deviation); continuous variables between two groups were compared using Student’s -test, between , healthy group, and β, SLE; Gender and use of statins were compared using Fisher’s exact test; indicates value < 0.05.