Research Article

Lenalidomide and Low Dose Dexamethasone Plus Elotuzumab or Carfilzomib for Relapsed or Refractory Multiple Myeloma: A Comparison of Progression-Free Survival with Reconstructed Individual Participant Data

Table 2

Baseline characteristics of patients.

CharacteristicsElotuzumab group Carfilzomib groupP value
(n=321)(n=396)

Age - yr
median6764NC
range37-8838-87

Male sex - no. ()192 (60)215 (54)0.16

ECOG performance status
0159 (50)165 (42)0.08
1138 (43)191 (48)
224 (8)40 (10)

Race - no.()
White264 (82)377 (95)< 0.000
Others57 (18)19 (5)

Time since diagnosis - mo
median41.636NC
range3.6-208.14.8-236.4

Disease stage (ISS) no. ()
I141 (44)64 (16)< 0.000
II102 (32)99 (25)
III66 (21)185 (47)
unkown12 (4)48 (12)

Previous therapy regimens
median no.(range)2 (1-4)2 (1-3)NC
regimens no.(%)
1151 (47)184 (47)0.96
2 or more170 (53)211 (53)

: statistically significant.
NC: not calculable.