Eosinophils from Physiology to Disease: A Comprehensive Review

Table 4

Diagnostic criteria for ABPA [23].

Hierarchy of criteria	Criteria for ABPA diagnosis
Major criteria; Both necessary, but not sufficient	Allergic sensitisation to A fumigatus: positive skin prick test or detectable or raised sIgE to A. fumigatus
	Elevated total IgE levels > 1000 kIU/l (=2400 μg/l)
Minor criteria; Two or three are sufficient	Aspergillus IgG serology positive or raised, detection of anti-Aspergillus precipitins
	Radiology, according to the clinical stage: transient migratory pulmonary opacities to fixed central bronchiectasis
	Elevated circulating eosinophils > 0.5 or 1 × 10^9/l
Background	Asthma, cystic fibrosis