Radiotherapy for Adult Medulloblastoma: Evaluation of Helical Tomotherapy, Volumetric Intensity Modulated Arc Therapy, and Three-Dimensional Conformal Radiotherapy and the Results of Helical Tomotherapy Therapy
Table 1
General characteristics of the patients and the radiotherapy-related parameters.
Category
Patients
Patient 1
Patient 2
Patient 3
Patient 4
Patient 5
General characteristics
Gender
Male
Male
Female
Female
Female
Age (year)
30
25
28
18
23
Tumor location
Cerebellopontine angle area
Fourth cerebral ventricle
Cerebellum
Cerebellar vermis
Cerebellar vermis
Neurological examination
Negative
Negative
-
Negative
Negative
Tumor size (cm)
3.0 × 3.1
2.4 × 3.6
-
3.5 × 4.3
2.8 × 3.0
Histological features
Group 4
Group 4
-
Group 4
Group 4
Extension of tumor
Cerebellum
Third ventricle of cerebrum
-
Fourth cerebral ventricle
Fourth cerebral ventricle
The amount of surgical removal (cm)
3.0 × 3.0 × 2.0
4.0 × 6.0 × 3.0
-
4.5 × 4.5 × 3.0
3.5 × 3.5 × 3.0
MRI
Brain MRI/tumor residual
Yes/no
Yes/yes
Yes/no
Yes/no
Yes/no
Spinal cord MRI/metastasis
Yes/no
Yes/yes
No/-
No/-
No/-
Posttreatment MRI/progressive disease
Yes/no
-#
Yes/no
Yes/no
Yes/no
Radiotherapy-related parameters
TM stage
T2M0
T4M3
TXMX
T2MX
T3aMX
Prescription dose (Gy/F)
PTV1
30.6/17
35/20
30.6/17
36/20
36/20
PTV2
19.8/11
18/10
23.4/13
18/10
18/10
Interruption/cause
Yes/ bone suppression
Yes/ vacation, pain
Yes/ machine breakdown
Yes/ bone suppression
No/-
Interruption time (day)
4
5
2
3
0
: the patient underwent surgery at another hospital in Shanghai City, and the pathology data cannot be obtained, and the histological characteristics of the patient cannot be furtherly determined; : the patient abandoned treatment after 7 fractions of radiotherapy and had no MRI reexamination. And the patient died in July 2017.
