Chemokine C-C Motif Ligand 4 Gene Polymorphisms Associated with Susceptibility to Rheumatoid Arthritis

Table 1

Demographic profiles of the study participants.

Variable	Controls (N=371)	RA patients (N=217)	p value
Age
≦60 years	297 (80.1%)	147 (67.7%)	0.001
>60 years	74 (19.9%)	70 (32.3%)
Gender
Female	209 (56.3%)	181(83.4%)	<0.001
Male	162 (43.7%)	36 (16.6%)
RF-positive		33 (15.2%)
ESR
<20 mm/h		108 (49.8%)
≧20 mm/h		109 (50.2%)
TNF inhibitor
NO		131 (60.4%)
YES		86 (39.6%)
Methotrexate
NO		95 (43.8%)
YES		122 (56.2%)
Prednisolone
NO		98 (45.2%)
YES		119 (54.8%)

RA: rheumatoid arthritis; RF: rheumatoid factor; ESR: erythrocyte sedimentation rate; TNF: tumor necrosis factor.