BioMed Research International / 2018 / Article / Tab 2

Research Article

Chemokine C-C Motif Ligand 4 Gene Polymorphisms Associated with Susceptibility to Rheumatoid Arthritis

Table 2

Polymorphism frequencies among the study participants.

SNPsControlsRA patientsOR (95% CI)AOR (95% CI)
(N=371)(N=217)

rs10491121
 A/A94 (25.3%)54 (24.9%)1.001.00
 A/G175 (47.2%)105 (48.4%)1.04 (0.69-1.58)0.82 (0.53-1.28)
 G/G102 (27.5%)58 (26.7%)0.99 (0.62-1.58)0.91 (0.56-1.49)
 A/G+G/G277 (77.7%)163 (75.1%)1.02 (0.70-1.51)0.85 (0.56-1.27)
rs1719153
 A/A162 (43.7%)80 (36.9%)1.001.00
 A/T164 (44.2%)108 (49.8%)1.33 (0.93-1.91)0.67 (0.46-0.99)#
 T/T45 (12.1%)29 (13.4%)1.31 (0.76-2.24)0.77 (0.44-1.35)
 A/T+T/T209 (56.3%)137 (63.2%)1.33 (0.94-1.87)0.69 (0.48-0.99)#
rs1634507
 C/C161 (43.4%)90 (41.5%)1.001.00
 A/C165 (44.5%)98 (45.2%)1.06 (0.74-1.52)0.81 (0.55-1.19)
 A/A45 (12.1%)29 (13.4%)1.15 (0.68-1.97)0.89 (0.51-1.57)
 A/C+A/A210 (56.6%)127 (58.6%)1.08 (0.77-1.52)0.83 (0.58-1.19)

Data are represented as N (%).
#p< 0.05.
SNP: single nucleotide polymorphism; RA: rheumatoid arthritis; OR: odds ratio; CI: confidence interval; AOR: adjusted odds ratio.

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