Chemokine C-C Motif Ligand 4 Gene Polymorphisms Associated with Susceptibility to Rheumatoid Arthritis

Table 3

Frequencies of CCL4 rs1719153 polymorphisms among RA patients, stratified by medications, RF, and ESR status.

Variables; (general population)		A/A	A/T + T/T	AOR (95% CI)
TNF-α inhibitor	No	48	83	1
	Yes	32	54	0.98 (0.56-1.71)
Methotrexate	No	38	57	1
	Yes	43	80	1.27 (0.73-2.21)
Prednisolone	No	33	65	1
	Yes	47	72	0.78 (0.45-1.36)
RF	Negative	13	20	1
	Positive	67	117	1.14 (0.53-2.43)
ESR (mm/h)	< 20	36	72	1
	> 20	44	65	0.74 (0.43-1.29)

RA: rheumatoid arthritis; RF: rheumatoid factor; ESR: erythrocyte sedimentation rate; CI: confidence interval; AOR: adjusted odds ratio; TNF-α: tumor necrosis factor-alpha.