Research Article
Chemokine C-C Motif Ligand 4 Gene Polymorphisms Associated with Susceptibility to Rheumatoid Arthritis
Table 4
Polymorphism frequencies among the female participants.
| | Variable | Control females | RA females | OR (95% CI) | AOR (95% CI) | | | (N=209) | (N=181) | | |
| | rs10491121 | | | | | | A/A | 64 (30.6%) | 44 (24.3%) | 1.00 | 1.00 | | A/G | 92 (44.0%) | 88 (48.6%) | 1.39 (0.86-2.25) | 0.70 (0.43-1.14) | | G/G | 53 (25.4%) | 49 (27.1%) | 1.35 (0.78-2.32) | 0.76 (0.44-1.32) | | A/G+G/G | 145 (69.4%) | 137 (72.3%) | 1.37 (0.88-2.15) | 0.72 (0.45-1.14) | | rs1719153 | | | | | | A/A | 101 (48.3%) | 64 (35.4%) | 1.00 | 1.00 | | A/T | 83 (39.7%) | 90 (49.7%) | 1.71 (1.11-2.64)# | 0.56 (0.36-0.88)# | | T/T | 25 (12.0%) | 27 (14.9%) | 1.70 (0.91-3.19) | 0.60 (0.31-1.13) | | A/T+T/T | 108 (51.7%) | 117 (64.6%) | 1.71 (1.14-2.57)# | 0.57 (0.38-0.87)## | | rs1634507 | | | | | | C/C | 101 (48.3%) | 75 (41.4%) | 1.00 | 1.00 | | A/C | 81 (38.8%) | 81 (44.8%) | 1.35 (0.88-2.07) | 0.72 (0.46-1.11) | | A/A | 27 (12.9%) | 25 (13.8%) | 1.25 (0.67-2.32) | 0.86 (0.46-1.63) | | A/C+A/A | 108 (51.7%) | 106 (58.6%) | 1.32 (0.89-1.97) | 0.75 (0.50-1.13) |
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p < 0.05; ##p < 0.01. RA: rheumatoid arthritis; OR: odds ratio; CI: confidence interval; AOR: adjusted odds ratio. |
