A Prospective, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study Evaluating Meniscal Healing, Clinical Outcomes, and Safety in Patients Undergoing Meniscal Repair of Unstable, Complete Vertical Meniscal Tears (Bucket Handle) Augmented with Platelet-Rich Plasma

Table 4

Secondary outcome assessment at 42 months (pain: VAS and KOOS-pain; function: IKDC, WOMAC, KOOS-symptom, KOOS-ADL, KOOS-sport/recreation, and KOOS-QOL).

	Control group	PRP-treated group	value
VAS score	0.89 ± 0.08 (0.33–1.44)	0.84 ± 0.10 (0.04–1.65)
IKDC score	84.77 ± 0.92 (78.24–91.29)	97.56 ± 0.63 (92.62–102.49)
WOMAC	3.95 ± 0.33 (1.58−6.31)	0.95 ± 0.13 (−0.07–1.96)	= 0.002
KOOS score
(i) Pain	92.85 ± 0.43 (89.83–95.87)	96.06 ± 0.23 (94.22–97.91)
(ii) Symptoms	92.33 ± 0.48 (88.94–95.73)	96.23 ± 0.31 (93.79–98.67)
(iii) ADL	95.14 ± 0.38 (92.47–97.81)	98.18 ± 0.13 (98.13–100.24)
(iv) Sport/recreation	77.65 ± 1.26 (68.73–86.56)	89.44 ± 0.86 (82.68–96.21)
(v) QOL	66.18 ± 1.17 (57.94–74.42)	80.90 ± 1.09 (72.34–89.47)

Data are presented as mean ± standard error (95% confidence interval); VAS, visual analog scale; KOOS, Knee Injury and Osteoarthritis Outcome Score; IKDC, International Knee Documentation Committee; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index; ADL, activities of daily living; QOL, quality of life; PRP, platelet-rich plasma.