Association of Resistin Gene Polymorphisms with Oral Squamous Cell Carcinoma Progression and Development
Table 1
Demographic and clinical characteristics of 1,200 cancer-free, healthy males (controls) and 935 Taiwanese male patients with oral squamous cell carcinoma.
Variable
Controls (N=1,200)
Patients (N=935)
p-value
Age (years)
≤54
566 (47.2%)
453 (48.5%)
p=0.556
>54
634 (52.8%)
482 (51.5%)
Betel quid chewing
No
1,001 (83.4%)
190 (20.3%)
Yes
199 (16.6%)
745 (79.7%)
p <0.001
Cigarette smoking
No
564 (47.0%)
106 (11.3%)
Yes
636 (53.0%)
829 (88.7%)
p <0.001
Alcohol drinking
No
963 (80.3%)
440 (47.1%)
Yes
237 (19.7%)
495 (52.9%)
p <0.001
Histological grade
I+II
466 (49.8%)
III+IV
469 (50.2%)
Tumor status (T)
T1+T2
540 (57.8%)
T3+T4
395 (42.2%)
Lymph node metastasis (N)
N0
628 (67.2%)
N1+N2+N3
307 (32.8%)
Distal metastasis (M)
M0
926 (99.0%)
M1
9 (1.0%)
Cell differentiation
Well differentiated
139 (14.9%)
Moderately or poorly differentiated
796 (85.1%)
The Mann-Whitney U test or Fisher’s exact test was used to compare values between healthy controls and patients with OSCC. p value < 0.05 was considered statistically significant.
