Autophagy Is Independent of the Chondroprotection Induced by Platelet-Rich Plasma Releasate

Figure 4

Effect of PRP on normal chondrocytes or IL-1-treated chondrocytes with autophagy activation. (a, c) The expression of Aggrecan, COL2, ADAMTS5, and MMP13 in chondrocytes was measured by RT-PCR. (b, d) The expression of LC3 II/LC3 I, Atg5, and Beclin 1 was analyzed by western blot. represents significant difference versus control group; # represents significant difference versus IL-1β group.

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