Neuropeptide B and Vaspin as New Biomarkers in Anorexia Nervosa

Table 2

Characteristics of ROC curves for adjusted serum neuropeptide B, vaspin, and Total Antioxidant Status levels according Body Mass Index for pairs of studied groups (AN; n=46 versus CONTR; n=30).

Parameter [unit]	Sensitivity	Specificity	Cut-off value	AUC	SD (AUC)	95% CI	P
Adjusted neuropeptide B [ng/mL/kg/m^2]	91%	37%	14.67	0.700	0.060	0.581-0.819	<0.001
Adjusted vaspin [ng/mL/kg/m^2]	87%	50%	0.02	0.647	0.067	0.516-0.777	<0.003
Adjusted Total Antioxidant Status [mmol/L/kg/m^2]	52%	75%	0.06	0.583	0.065	0.456-0.711	NS

AN: group with anorexia nervosa; CONTR: control group; n: number of persons; cut-off value: point on ROC (Receiver Operating Characteristic) curve; AUC: Area Under Curve of Receiver Operating Characteristic curve; SD (AUC): standard deviation of AUC; p: level of statistical significance; NS: not statistically significant difference.