Research Article
Association between Low Free Triiodothyronine Levels and Poor Prognosis in Patients with Acute ST-Elevation Myocardial Infarction
Table 1
Baseline characteristics of the patients.
| | | Low fT3 () | Normal fT3 () | | Adjusted |
| | Age (years) | 68 (59–76) | 61 (50–71) | <0.001 | <0.001 | | Male gender, (%) | 113 (63.1) | 390 (82.5) | <0.001 | 0.071 | | Current smoker, (%) | 63 (35.2) | 253 (53.5) | <0.001 | 0.568 | | History of hypertension, (%) | 88 (49.2) | 206 (43.6) | 0.199 | 0.939 | | Diabetes, (%) | 42 (23.5) | 93 (19.7) | 0.285 | 0.523 | | Previous MI, (%) | 6 (3.4) | 15 (3.2) | 0.907 | 0.884 | | SBP (mmHg) | 112 (99–128) | 119 (106–132) | 0.003 | <0.001 | | DBP (mmHg) | 70 (61–79) | 71 (64–82) | 0.038 | 0.050 | | Heart rate (bpm) | 86 (74–102) | 78 (68–90) | <0.001 | <0.001 | | Killip class on admission, (%) | | | <0.001 | <0.001 | | I | 67 (37.4) | 343 (72.5) | | | | II | 38 (21.2) | 78 (16.5) | | | | III | 32 (17.9) | 17 (3.6) | | | | IV | 42 (23.5) | 35 (7.4) | | | | LVEF (%) | 58 (48–61) | 59 (55–62) | 0.001 | 0.001 | | fT3 (pmol/L) | 2.5 (2.3–2.8) | 3.8 (3.4–4.2) | <0.001 | <0.001 | | fT4 (pmol/L) | 14.8 (13–17.1) | 15.2 (13.6–17.1) | 0.018 | 0.001 | | TSH (mIU/L) | 1.17 (0.65–2.05) | 1.47 (0.79–2.43) | 0.007 | 0.003 | | Serum creatinine (μmol/L) | 80.9 (64.1–112.9) | 73.5 (62.8–88.9) | <0.001 | <0.001 | | BNP (pg/ml) | 745.5 (389.5–1585.0) | 257.0 (90.0–574.3) | <0.001 | <0.001 | | TnI (ng/ml) | 11.5 (4.6–22.4) | 8.0 (2.4–20.1) | 0.017 | 0.050 | | TC (mmol/L) | 4.08 (3.26–4.71) | 4.32 (3.63–5.02) | 0.003 | 0.005 | | LDL-C (mmol/L) | 2.40 (1.90–3.04) | 2.64 (2.15–3.16) | 0.003 | 0.006 | | TG (mmol/L) | 1.22 (0.96–1.66) | 1.48 (1.10–2.09) | <0.001 | <0.001 | | HDL-C (mmol/L) | 0.97 (0.81–1.17) | 0.94 (0.80–1.13) | 0.424 | 0.453 | | Hemoglobin (g/L) | 121 (108–134) | 134 (122–145) | <0.001 | <0.001 | | Reperfusion therapy, (%) | 90 (50.3) | 342 (72.3) | <0.001 | 0.001 | | Thrombolytic therapy, (%) | 24 (13.4) | 68 (14.4) | 0.751 | 0.497 | | Primary PCI, (%) | 66 (36.9) | 274 (57.9) | <0.001 | <0.001 | | Aspirin, (%) | 173 (96.65) | 466 (98.52) | 0.204 | 0.438 | | Clopidogrel/Ticagrelor, (%) | 175 (97.77) | 468 (98.94) | 0.268 | 0.588 | | β-receptor blocker, (%) | 140 (78.21) | 388 (82.03) | 0.268 | 0.659 | | Statin, (%) | 165 (92.18) | 449 (94.93) | 0.181 | 0.257 | | ACEI/ARB, (%) | 144 (80.45) | 407 (86.05) | 0.078 | 0.134 |
|
|
Adjusted for age and sex. Adjusted for sex. Adjusted for age. MI: myocardial infarction; SBP: systolic blood pressure; DBP: diastolic blood pressure; LVEF: left ventricular ejection fraction; fT3: free triiodothyronine; fT4: free thyroxine; TSH: thyroid-stimulating hormone; BNP: brain natriuretic peptide; TnI: troponin I; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; PCI: percutaneous coronary intervention; ACEI: angiotensin converting enzyme inhibitor; ARB: angiotensin II receptor blocker. |
