Research Article

Direct Intrahepatic Portocaval Shunt for Sinusoidal Obstruction Syndrome Associated with Hepatotoxicity of Pyrrolizidine Alkaloids

Table 1

Baseline characteristics of SOS cases.

Characteristic/groupAB value

Gender M/F30/389/120.366
Age (mean (S.D.))38.98±19.3435.25±8.640.299
Child-PughA/B/C3/55/101/11/90.328
MELD score (mean (S.D.))12.49±7.2513.17±9.160.145
Accompanied viral hepatitis530.628
Chronic ethanol consumption600
Cryptogenic hepatitis200
Variceal hemorrhage(VH)3050.217
Refractory ascites(RA)65140.134
Both VH and RA2520
Laboratory tests
 Alanine transaminase249.73±192.12182.05±81.300.595
 Aspartate transaminase383.98±289.49301.05±214.010.604
 Alkaline phosphatase258.32±163.24264.43±176.910.371
 Gamma glutamyl transpeptidase276.45±125.34297.39±136.730.256
 Total bilirubin25.44±10.9926.31±10.910.192
 Albumin29.37±9.2528.61±9.720.261
 Prothrombin time16.24±7.6918.15±8.460.135
Clinical presentations
 Abdominal distention67180.154
 Abdominal pain24130.364
 Weakness51160.412
 Poor appetite63190.346
 Jaundice48120.216
 Hepatomegaly65180.423
 Splenomegaly31130.338
 Pleural effusion250
 Lower limbs edema1230.026
Endoscopic therapy48150.128
Asites paracentesis154340.093
Seattle criteria24130.364
Baltimore criteria1890.379

No difference (P>0.05) could be seen in terms of age, sex, Child–Pugh score, and MELD score; laboratory tests, and clinical presentations. MELD, Model of End-stage Liver Disease; RA, refractory ascites; VH, variceal hemorrhage; laboratory tests and clinical presentations.