Research Article

Contrast-Enhanced Ultrasound Improves the Pathological Outcomes of US-Guided Core Needle Biopsy That Targets the Viable Area of Anterior Mediastinal Masses

Table 1

Baseline characteristics, prebiopsy ultrasonographic features, and outcomes of 92 patients with AMMs who underwent initial US-CNB with prebiopsy conventional US or CEUS evaluation.

US CEUS value

Age (years), mean ± SD0.763
Gender, male/female50/2514/30.207
Cancer history yes/no3/752/170.205
Location of AMMs (both/left/right)8/40/270/10/70.408
Size of AMMs (mm), mean ± SD0.721
CDFI category (marked/not marked)29/463/140.074
Marginal blood flow signals (presence/absence)47/2815/20.043
Necrosis (presence/absence)8/675/120.046
Punctures of core needle (mean ± SD)0.333
Repeated US-guided CNB (no/yes)17/580/170.031
Conclusive histological diagnoses (no/yes)20/551/160.067
Cellularity (mean ± SD)0.001
Lung tissue in the sample (presence/absence)6/690/170.144
Duration between initial CNB and treatment decision (days mean ± SD)<0.001

US, ultrasound; US-CNB, ultrasound-guided core needle biopsy; AMM, anterior mediastinal mass; CEUS, contrast-enhanced ultrasound; SD, standard deviation.