Review Article
Onco-Multi-OMICS Approach: A New Frontier in Cancer Research
Table 1
Different omics techniques and their applications.
| Omics | Type | Principle | Throughput | Application |
| Genomics | Whole exome sequencing | NGS | high | Genome-wide mutational/ analysis |
| | Whole genome sequencing | NGS | high | Exome-wide mutational analysis |
| | Targeted gene/exome sequencing | Sanger-sequencing | Low | Mutational analysis in targeted gene/exon |
| Epigenomics | Methylomics | Whole-genome bisulfite sequencing | High | Genome-wide mapping of DNA methylation pattern | ChIP-sequencing | Chromatin IP∗ and NGS | high | Genome-wide mapping of epigenetic marks |
| Transcriptomics | RNA-sequencing | NGS | High | Genome-wide differential gene expression analysis | microarray | Hybridization | High | Differential gene expression analysis |
| Proteomics | RPPA | Antibody based | Low | Differential protein abundance analysis | Deep-proteomics | Mass-spectrometry | high | Genome-wide differential protein expression analysis |
| Metabolomics | Deep-metabolomics | Mass-spectrometry | high | Differential metabolite expression analysis |
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