BioMed Research International / 2018 / Article / Tab 1

Review Article

Onco-Multi-OMICS Approach: A New Frontier in Cancer Research

Table 1

Different omics techniques and their applications.

OmicsTypePrincipleThroughputApplication

GenomicsWhole exome sequencingNGShighGenome-wide mutational/ analysis

Whole genome sequencingNGShighExome-wide mutational analysis

Targeted gene/exome sequencingSanger-sequencingLowMutational analysis in targeted gene/exon

EpigenomicsMethylomicsWhole-genome bisulfite sequencingHighGenome-wide mapping of DNA methylation pattern
ChIP-sequencingChromatin IP∗ and NGShighGenome-wide mapping of epigenetic marks

TranscriptomicsRNA-sequencingNGSHighGenome-wide differential gene expression analysis
microarrayHybridizationHighDifferential gene expression analysis

ProteomicsRPPAAntibody basedLowDifferential protein abundance analysis
Deep-proteomicsMass-spectrometryhighGenome-wide differential protein expression analysis

MetabolomicsDeep-metabolomicsMass-spectrometryhighDifferential metabolite expression analysis

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