|
| | | E14 vs. P90 | | E16 vs. P90 | | P1 vs. P90 |
Gene symbol | Full gene name and probe set | | Stepup P-value | Fold change | | Stepup P-value | Fold change | | Stepup P-value | Fold change |
|
Production of precursors |
Galk1 | Galactokinase 1 | | 0.030 | 4.242 | | 0.126 | 2.483 | | 0.231 | 2.194 |
| 6792485 | | | | | | | | | |
Galt | Gal-1-P-Uridylyltransferase | | 0.664 | 0.814 | | 0.231 | 1.864 | | 0.665 | 1.340 |
| 6912944 | | | | | | | | | |
Gfpt1 | Glu-Fru-6-P-Transaminase 1 | | 0.020 | 2.110 | | 0.077 | 1.682 | | 0.801 | 1.081 |
| 6947679 | | | | | | | | | |
Gfpt2 | Glu-Fru-6-P-Transaminase 2 | | 0.176 | 0.610 | | 0.087 | 0.426 | | 0.229 | 0.547 |
| 6780767 | | | | | | | | | |
Hk2 | Hexokinase 2 | | 0.003 | 0.451 | | 0.040 | 1.375 | | 0.039 | 0.655 |
| 6954982 | | | | | | | | | |
Pgm3 | Phosphoglucomutase 2 | | 0.083 | 2.193 | | 0.676 | 1.178 | | 0.654 | 1.286 |
| 6997513 | | | | | | | | | |
Pgm5 | Phosphoglucomutase 5 | | 0.058 | 2.338 | | 0.104 | 2.209 | | 0.291 | 1.696 |
| 6872290 | | | | | | | | | |
Slc13a5 | Solute Carrier Family 13 Member A5 | | 0.003 | 2.588 | | 0.059 | 1.322 | | 0.576 | 1.075 |
| 6789531 | | | | | | | | | |
Slc26a9 | Solute Carrier Family 26 Member A9 | | 0.012 | 0.227 | | 0.090 | 0.471 | | 0.091 | 0.392 |
| 6753079 | | | | | | | | | |
Slc35a3 | Solute Carrier Family 35 Member A3 | | 0.105 | 0.767 | | 0.596 | 0.925 | | 0.572 | 0.890 |
| 6908510 | | | | | | | | | |
|
Core proteins |
Cd44 | CD44 Molecule | | 0.009 | 0.370 | | 0.144 | 0.728 | | 0.873 | 0.955 |
| 6889258 | | | | | | | | | |
Gpc2 | Glypican 2 | | Not measured | | Not measured | | Not measured |
Gpc3 | Glypican 3 | | 0.003 | 4.339 | | 0.013 | 3.305 | | 0.015 | 4.721 |
| 7016826 | | | | | | | | | |
Gpc6 | Glypican 6 | | 0.019 | 2.767 | | 0.109 | 1.747 | | 0.193 | 1.640 |
| 6821985 | | | | | | | | | |
Hspg2 | Perlecan | | 0.309 | 1.183 | | 0.075 | 1.554 | | 0.042 | 2.230 |
| 6917933 | | | | | | | | | |
Sdc1 | Syndecan 1 | | 0.031 | 0.380 | | 0.067 | 0.413 | | 0.103 | 0.424 |
| 6793226 | | | | | | | | | |
Sdc4 | Syndecan 4 | | 0.017 | 0.341 | | 0.094 | 0.536 | | 0.215 | 0.621 |
| 6892905 | | | | | | | | | |
|
Preparation of linkage region |
B3gat1 | β-1,3-Glucuronyltransferase 1 | | 0.008 | 3.467 | | 0.256 | 1.302 | | 0.828 | 0.929 |
| 6987632 | | | | | | | | | |
B3gat2 | β-1,3-Glucuronyltransferase 2 | | 0.009 | 3.241 | | 0.286 | 1.269 | | 0.690 | 1.129 |
| 6748174 | | | | | | | | | |
B4galt2 | β-1,4-Galactosyltransferase 2 | | 0.039 | 1.726 | | 0.053 | 1.856 | | 0.176 | 1.477 |
| 6924869 | | | | | | | | | |
|
Glycosaminoglycan chain polymerisation |
Chpf | Chondroitin Polymerizing Factor | | 0.071 | 1.679 | | 0.182 | 1.459 | | 0.309 | 1.403 |
| 6759816 | | | | | | | | | |
Chsy1 | CS Synthase 1 | | Not measured | | Not measured | | Not measured |
Chsy3 | CS Synthase 3 | | 0.429 | 1.153 | | 0.056 | 1.769 | | 0.849 | 1.058 |
| 6861281 | | | | | | | | | |
Cs-galnact1 | CS-GalNAc-transferase 1 | | 0.137 | 0.512 | | 0.202 | 0.541 | | 0.974 | 0.975 |
| 6983073 | | | | | | | | | |
Extl1 | Exostoses (multiple)-like 1 | | 0.025 | 0.407 | | 0.149 | 0.625 | | 0.144 | 0.505 |
| 6926017 | | | | | | | | | |
Extl2 | Exostoses (multiple)-like 2 | | 0.085 | 1.702 | | 0.819 | 1.066 | | 0.518 | 1.272 |
| 6900659 | | | | | | | | | |
Has2 | Hyaluronan Synthase 2 | | 0.095 | 2.107 | | 0.157 | 1.969 | | 0.537 | 1.403 |
| 6854042 | | | | | | | | | |
|
Glycosaminoglycan chain modification |
Chst11 | Chondroitin 4-O-Sulfotransferase 1 | | 0.049 | 1.922 | | 0.465 | 1.208 | | 0.239 | 1.531 |
| 6769366 | | | | | | | | | |
Chst14 | Dermatan 4 Sulfotransferase 1 | | 0.151 | 1.491 | | 0.506 | 1.191 | | 0.773 | 1.122 |
| 6880476 | | | | | | | | | |
Chst2 | Carbohydrate Sulfotransferase 2 | | 0.035 | 2.302 | | 0.072 | 2.160 | | 0.207 | 1.682 |
| 6997990 | | | | | | | | | |
Chst3 | Chondroitin 6-O-Sulfotransferase 1 | | 0.885 | 1.034 | | 0.108 | 1.545 | | 0.162 | 1.530 |
| 6774295 | | | | | | | | | |
Chst8 | GalNAc-4-O-Sulfotransferase 1 | | 0.945 | 1.007 | | 0.569 | 1.054 | | 0.420 | 1.108 |
| 6966453 | | | | | | | | | |
Hs3st1 | HS 3-O-sulfotransferase 1 | | 0.074 | 1.658 | | 0.105 | 1.688 | | 0.119 | 1.824 |
| 6937654 | | | | | | | | | |
Hs3st3b1 | HS 3-O-sulfotransferase 3b1 | | 0.683 | 1.178 | | 0.253 | 1.634 | | 0.511 | 1.432 |
| 6788991 | | | | | | | | | |
Hs3st6 | HS 3-O-sulfotransferase 6 | | 0.019 | 0.406 | | 0.291 | 0.771 | | 0.721 | 1.130 |
| 6849317 | | | | | | | | | |
Hs6st2 | HS 6O-sulfotransferase 2 | | 0.004 | 6.417 | | 0.012 | 5.609 | | 0.041 | 3.080 |
| 7016808 | | | | | | | | | |
Ndst1 | N-Deacetylase and N-Sulfotransferase 1 | | 0.090 | 1.363 | | 0.056 | 1.649 | | 0.067 | 1.763 |
| 6865926 | | | | | | | | | |
Ndst2 | N-Deacetylase and N-Sulfotransferase 2 | | 0.822 | 1.044 | | 0.059 | 1.697 | | 0.083 | 1.733 |
| 6823122 | | | | | | | | | |
Ndst3 | N-Deacetylase and N-Sulfotransferase 3 | | 0.173 | 2.472 | | 0.111 | 3.856 | | 0.122 | 4.860 |
| 6908958 | | | | | | | | | |
Sulf1 | Sulfatase 1 | | 0.010 | 4.522 | | 0.051 | 2.546 | | 0.232 | 1.627 |
| 6747641 | | | | | | | | | |
Sumf2 | Sulfatase modifying factor 2 | | Not measured | | Not measured | | Not measured |
|
Glycosaminoglycan chain degradation |
ArsJ | Arylsulfatase J | | 0.003 | 2.498 | | 0.006 | 3.164 | | 0.031 | 1.702 |
| 6901136 | | | | | | | | | |
ArsK | Arylsulfatase K | | 0.368 | 0.784 | | 0.102 | 0.543 | | 0.514 | 0.779 |
| 6814451 | | | | | | | | | |
Galns | Galactosamine (N-Acetyl)-6-Sulfatase | | 0.087 | 1.671 | | 0.322 | 1.311 | | 0.786 | 1.115 |
| 6985943 | | | | | | | | | |
Hpse | Heparanase | | 0.021 | 0.267 | | 0.540 | 1.244 | | 0.095 | 0.360 |
| 6940363 | | | | | | | | | |
Hyal1 | Hyaluronoglucosamini-dase 1 | | 0.003 | 0.154 | | 0.011 | 0.222 | | 0.041 | 0.402 |
| 6992224 | | | | | | | | | |
Sgsh | N-Sulfoglucosamine Sulfohydrolase | | 0.017 | 0.458 | | 0.052 | 0.537 | | 0.201 | 0.699 |
| 6792702 | | | | | | | | | |
|
Growth factors |
Areg | Amphiregulin | | 0.016 | 0.157 | | 0.043 | 0.200 | | 0.333 | 0.550 |
| 6932394 | | | | | | | | | |
Bmp3 | Bone morphogenetic growth factor 3 | | 0.280 | 1.392 | | 0.067 | 2.381 | | 0.100 | 2.365 |
| 6932718 | | | | | | | | | |
Bmp5 | Bone Morphogenetic growth factor 5 | | 0.001 | 7.247 | | 0.141 | 1.191 | | 0.688 | 1.057 |
| 6990569 | | | | | | | | | |
Ctgf | Connective tissue growth factor | | 0.148 | 0.729 | | 0.025 | 0.366 | | 0.068 | 0.485 |
| 6766623 | | | | | | | | | |
Fgf10 | Fibroblast growth factor 10 | | 0.138 | 1.521 | | 0.057 | 2.250 | | 0.094 | 2.142 |
| 6810592 | | | | | | | | | |
Fgf13 | Fibroblast growth factor 13 | | 0.012 | 2.998 | | 0.075 | 1.824 | | 0.296 | 1.391 |
| 7017134 | | | | | | | | | |
Fgf2 | Fibroblast growth factor 2 | | 0.201 | 0.664 | | 0.279 | 0.696 | | 0.952 | 0.967 |
| 6896850 | | | | | | | | | |
Fgf20 | Fibroblast growth factor 20 | | 0.659 | 1.228 | | 0.125 | 2.483 | | 0.777 | 1.220 |
| 6981854 | | | | | | | | | |
Fgf22 | Fibroblast growth factor 22 | | 0.005 | 0.329 | | 0.972 | 0.994 | | 0.097 | 0.646 |
| 6769141 | | | | | | | | | |
Fgf7 | Fibroblast growth factor 7 | | 0.531 | 0.740 | | 0.078 | 0.286 | | 0.212 | 0.418 |
| 6880900 | | | | | | | | | |
Fgf8 | Fibroblast growth factor 8 | | 0.492 | 0.883 | | 0.655 | 1.085 | | 0.682 | 0.895 |
| 6873363 | | | | | | | | | |
Figf | C-fos induced growth factor | | 0.051 | 1.734 | | 0.062 | 1.909 | | 0.548 | 0.832 |
| 7015007 | | | | | | | | | |
Gdf10 | Growth differentiation factor 10 | | 0.028 | 2.334 | | 0.757 | 1.086 | | 0.894 | 1.060 |
| 6818153 | | | | | | | | | |
Hbegf | Heparin-binding epidermal growth factor | | 0.037 | 0.551 | | 0.063 | 0.547 | | 0.087 | 0.530 |
| 6864680 | | | | | | | | | |
Hdgf | Hepatoma-derived growth factor | | 0.104 | 1.246 | | 0.575 | 1.070 | | 0.409 | 1.147 |
| 6899028 | | | | | | | | | |
Igf1 | Insulin-like growth factor 1 | | 0.235 | 0.631 | | 0.173 | 0.537 | | 0.398 | 0.641 |
| 6769597 | | | | | | | | | |
Igf2 | Insulin-like growth factor 2 | | 0.001 | 59.615 | | 0.002 | 55.864 | | 0.002 | 52.364 |
| 6972317 | | | | | | | | | |
Nog | Noggin | | 0.275 | 2.605 | | 0.517 | 1.773 | | 0.677 | 1.712 |
| 6790670 | | | | | | | | | |
Pdgfa | Platelet-derived growth factor a | | 0.028 | 2.013 | | 0.035 | 2.347 | | 0.057 | 2.338 |
| 6942654 | | | | | | | | | |
Pdgfb | Platelet-derived growth factor b | | 0.037 | 0.704 | | 0.199 | 1.197 | | 0.157 | 1.298 |
| 6837144 | | | | | | | | | |
Pdgfc | Platelet-derived growth factor c | | 0.019 | 2.152 | | 0.035 | 2.207 | | 0.902 | 1.042 |
| 6898686 | | | | | | | | | |
Pdgfd | Platelet-derived growth factor d | | 0.925 | 0.952 | | 0.191 | 0.504 | | 0.790 | 1.205 |
| 6986677 | | | | | | | | | |
Shh | Sonic hedgehog | | 0.448 | 0.595 | | 0.308 | 2.117 | | 0.152 | 4.571 |
| 6936889 | | | | | | | | | |
Tgfb1 | Transforming growht factor beta 1 | | 0.106 | 0.552 | | 0.241 | 0.653 | | 0.975 | 0.981 |
| 6959236 | | | | | | | | | |
Tgfb2 | Transforming growht factor beta 2 | | 0.057 | 2.441 | | 0.448 | 1.335 | | 0.264 | 1.802 |
| 6764953 | | | | | | | | | |
Tgfb3 | Transforming growth factor beta 3 | | 0.026 | 2.386 | | 0.238 | 1.408 | | 0.100 | 2.077 |
| 6802449 | | | | | | | | | |
Vegfa | Vascular endothelial growth factor a | | 0.779 | 0.875 | | 0.721 | 1.174 | | 0.940 | 1.061 |
| 6855659 | | | | | | | | | |
Vegfb | Vascular endothelial growth factor b | | 0.008 | 1.461 | | 0.031 | 1.318 | | 0.060 | 1.277 |
| 6871273 | | | | | | | | | |
Vegfc | Vascular endothelial growth factor c | | 0.088 | 2.120 | | 0.477 | 1.316 | | 0.316 | 1.700 |
| 6976200 | | | | | | | | | |
Wnt10b | Wingless-related integration site 10b | | 0.629 | 1.280 | | 0.120 | 2.812 | | 0.240 | 2.325 |
| 6838399 | | | | | | | | | |
Wnt16 | Wingless-related integration site 16 | | 0.358 | 1.180 | | 0.026 | 2.402 | | 0.093 | 1.710 |
| 6944581 | | | | | | | | | |
Wnt2 | Wingless-related integration site 2 | | 0.057 | 3.047 | | 0.082 | 3.260 | | 0.122 | 3.219 |
| 6951974 | | | | | | | | | |
Wnt2b | Wingless-related integration site 2b | | 0.009 | 2.189 | | 0.024 | 2.030 | | 0.077 | 1.590 |
| 6907887 | | | | | | | | | |
Wnt3a | Wingless-related integration site 3a | | 0.457 | 1.199 | | 0.103 | 1.728 | | 0.684 | 1.159 |
| 6788662 | | | | | | | | | |
Wnt6 | Wingless-related integration site 6 | | 0.011 | 3.166 | | 0.032 | 2.668 | | 0.064 | 2.352 |
| 6750567 | | | | | | | | | |
Wnt7a | Wingless-related integration site 7a | | 0.060 | 2.117 | | 0.131 | 1.865 | | 0.395 | 1.456 |
| 6955539 | | | | | | | | | |
Wnt7b | Wingless-related integration site 7b | | 0.072 | 2.297 | | 0.050 | 3.623 | | 0.237 | 1.912 |
| 6837582 | | | | | | | | | |
|