Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development
Table 4
Differentially expressed genes in C5 epimerase (Glce) knockout mouse (p<0.10) based on real-time qPCR.
Gene symbol
Full gene name and probe set
P-value
Relative change
Production of precursors
Gnpnat1
Glucosamine-Phosphate N-Acetyltransferase 1
0.033
0.468
Mm00834602_mH
Slc2a4
Solute Carrier Family 2 Member 4
0.086
2.526
Mm01245507_g1
Core proteins
Acan
Aggrecan
0.005
0.242
Mm00545807_m1
Aspn
Asporin
0.010
0.382
Mm00445945_m1
Glycosaminoglycan chain polymerisation
Csgalnact
CS N-Acetylgalactosaminyltransferase 2
0.049
0.431
2
Mm00513340_m1
Glycosaminoglycan chain modification
Glce
Glucuronic Acid Epimerase
0.013
0.079
Mm00473667_m1
Numbers in Italic are significant (p<0.10); numbers in bold are >2 fold differentially expressed. All genes were normalized using 18S RNA as a reference gene.