BioMed Research International

Research Article

Effects of Diacetyl Flavoring Exposure in Mice Metabolism

Table 1

Coefficients of determination, equations, retention time (), MS, MS/MS, LD, LQ, linear range, CV, V, and IS.


Metabolites	R²	Equation	t_R	MS	MS/MS	LD	LQ	Linear range	CV	V	IS

5-HT	1	y = 0.015x- 0.020	1.27	241	60	0.42	1.40	5.00-400.00	28	18	Serotonin D₄
Ala	1	y = 0.007x - 0.037	1.62	225	44	0.05	0.18	20.00 - 600.00	22	10	Orn D₆
Ac-orn	0.99	y = 30.165x - 10.120	1.12	310	217	0.01	0.06	0.50 - 40.00	32	24	Orn D₆
ADMA	0.92	y = 0.0168x +-0.001	1.29	338	46	0.07	0.20	0.25 - 20.00	22	14	Ala D₄
Arg	0.99	y = 0.015x + 0.048	1.12	310	217	0.03	0.10	5.00 - 400.00	34	14	Arg ¹⁵N₂
Asn	1	y = 0.0149x + 0.024	1.18	268	87	0.01	0.05	5.00 - 400.00	20	16	Asn ¹⁵N₂
Asp	0.99	y = 0.010x - 0.987	1.41	269	116	0.01	0.03	5.00 - 400.00	24	14	Asp D₃
Car	1	y = 0.010x + 0.001	1.00	362	136	0.08	0.26	0.50 - 40.00	24	34	His ¹³C₆
Cit	1	y = 0.021x + 0.007	1.33	311	113	1.13	3.78	5.00 - 400.00	22	24	Cit ¹³C D₄
Cre	0.99	y = 0.008x + 0.041	0.16	114	44	0.72	2.42	10.00 - 800.00	32	14	Creatinine D₃
Dopa	0.99	y = 0.218x - 0.085	1.33	333	198	0.16	0.55	0.50 - 40.00	26	12	Dopa D₃
Gln	1	y = 0.019x + 0.006	1.22	282	130	0.03	0.12	20.00-1600.00	22	16	Gln D₅
Glu	0.99	y = 0.012x + 0.030	1.42	283	130	1.29	4.30	10.00 - 800.00	26	16	Glu D₃
Gly	1	y = 0.002x + 0.004	1.29	211	76	0.10	0.35	25.00- 2000.00	22	10	Gly ¹³C2 ¹⁵N
His	1	y = 0.018x + 0.004	1.00	291	110	0.76	2.55	5.00 - 400.00	22	22	His ¹³C₆
Hst	0.97	y= 0.110x - 0.078	1.01	247	154	0.03	0.11	5.00 - 400.00	22	12	His ¹³C₆
Ile	1	y = 0.001x - 0.001	2.51	267	69	0.15	0.52	5.00 - 400.00	24	28	Ile ¹³C₆
Kyn	0.99	y = 0.024x + 0.004	2.43	344	146	0.08	0.27	1.00 - 80.00	22	24	Tyr D₄
Leu	0.99	y = 2.542 e^{− 005}x + 2.791 e^{– 006}	2.51	267	43	0.06	0.02	5.00 - 400.00	24	38	Ile ¹³C₆
Lys	0.99	y = 0.037x - 0.512	2.50	417	324	0.07	0.26	10.00 - 800.00	26	12	Orn D₆
Met	1	y = 0.017x - 0.002	2.14	285	104	0.21	0.73	5.00 - 400.00	22	18	Met D₃
Met-So	0.98	y = 0.025x + 0.0435	1.34	301	88	0.01	0.05	1.00 - 80.00	18	30	Met D₃
Orn	0.98	y = 0.046x - 0.212	2.38	403	310	0.002	0.01	5.00 - 400.00	24	12	Orn D₆
Phe	0.99	y = 0.015x + 0.068	2.56	301	120	0.006	0.02	5.00 - 400.00	24	20	Phe D₅
Pro	0.99	y = 0.012x + 0.105	1.61	251	70	0.04	0.14	5.00 - 400.00	26	20	Pro D₇
Put	0.97	y=-0.033x +0.270	2.55	266	114	0,94	3.15	0.10 - 8.00	26	12	Putrescine D₄
Sar	1	y= 2.68x - 0.157	1.62	225	90	0.03	0.10	1.00 - 80.00	20	10	Sarcosine D₃
T4-OH-Pro	0.99	y= 0.009x - 0.005	1.29	267	132	0.01	0.06	1.00 - 80.00	24	14	Pro D₇
Tau	0.91	y= 0.016 x + 0.035	1.00	261	126	0.03	0.10	2.50 - 200.00	30	14	Taurine ¹³C₂
Thr	1	y = 0.020x + 0.020	1.53	255	73	0.07	0.26	5.00 - 400.00	22	18	Thr¹³C4 ¹⁵N
Trp	1	y = 0.015x - 0.015798	2.48	317	136	0.01	0.05	5.00 - 400.00	26	16	Trp ¹⁵N₂
Tyr	1	y= 0.0258201x +0.0219755	1.94	340	188	0.003	0.01	5.00 - 400.00	26	22	Tyr D₄
Val	0.99	y = 0.013x + 0.021	2.21	2534	72	0.01	0.06	10.00 - 800.00	24	16	Val D₈

min, (mol L^-1)