Extracorporeal Life Support: The Next Step in Moderate to Severe ARDS—A Review and Meta-Analysis of the Literature

Figure 4

In-hospital mortality: forest plots showing the subgroup pooled analysis of two RCTs when the ECLS modality was VV-ECMO (CESAR and EOLIA) (a) and VV-ECCO₂R (Morris and Bein) (b). The per-protocol analysis was used for the CESAR study. (a) Using a random-effects (RE) model: odds ratio (OR) = 2.23; 95% confidence interval (CI) = 0.18–28.07; I² = 92.74%; value for Q (PQ) < 0.001; (b) using a fixed-effects (FE) model: odds ratio (OR) = 1.29; 95% confidence interval (CI) = 0.54–3.10; I² = 14.22%; value for Q (PQ) = 0.80.

(a)

(b)