DCLK1 Plays a Metastatic-Promoting Role in Human Breast Cancer Cells

Figure 2

DCLK1 promotes breast cancer cells migration and invasion. (a) CRISPR/Cas9-mediated DCLK1 knockout was confirmed by western blot. (b) DCLK1 overexpression in T47D cells was confirmed by western blot. (c) Transwell migration and invasion assays in T47D cells overexpressing DCLK1 and their corresponding control cells. (d) Transwell analysis on the effect of DCLK1 deletion on cell migratory and invasive abilities of BT474 cell line. Results are exhibited as mean ± SD.

(a)

(b)

(c)

(d)