A Preliminary Study of Biliary Microbiota in Patients with Bile Duct Stones or Distal Cholangiocarcinoma

Table 2

Alpha diversity analysis of biliary microbiota in patients with dCCA and the onset of common bile duct stones.

Sample	mean (group_T)	sd (group_T)	mean (group_C)	sd (group_C)	mean (group_P)	sd (group_P)	value
Observed_OTU	209.6250	74.5576	165.0682	90.5750	134.2500	66.9423	0.0976
Chao	243.4245	73.2746	202.2659	94.6487	181.1733	71.3074	0.2413
Shannon	2.8807	1.1989	1.9514	1.1148	1.8863	0.8409	0.0989
Simpson	0.7738	0.2312	0.6270	0.2620	0.6687	0.2271	0.2010
Goodscoverage	0.9986	0.0006	0.9983	0.0008	0.9983	0.0008	0.8360
Shannoneven	0.5355	0.2064	0.3794	0.1877	0.3874	0.1515	0.0887

OTU, operational taxonomic unit; sd, Standard Deviation. The dCCA group (Tumor group, T), the new onset of CBD stones group (CBD stones group, C), and recurrent CBD stones group (Post-ERCP CBD stones group, P) denoted as “Group T”, “Group C”, and “Group P”, respectively, in the table.