CDK1, CCNB1, CDC20, BUB1, MAD2L1, MCM3, BUB1B, MCM2, and RFC4 May Be Potential Therapeutic Targets for Hepatocellular Carcinoma Using Integrated Bioinformatic Analysis

Table 3

Top 10 hub genes with the highest degree in the PPI network.

Gene symbol	Gene description	Degree
CDK1	Cyclin dependent kinase 1	49
CCNB2	Cyclin B2	48
CCNB1	Cyclin B1	48
CDC20	Cell division cycle 20	45
BUB1	BUB1 mitotic checkpoint serine/threonine kinase	44
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	44
MCM3	Minichromosome maintenance complex component 3	43
BUB1B	BUB1 mitotic checkpoint serine/threonine kinase B	42
MCM2	Minichromosome maintenance complex component 2	42
RFC4	Replication factor C subunit 4	41