Research Article

Intra-Articular versus Subacromial Corticosteroid Injection for the Treatment of Adhesive Capsulitis: A Meta-Analysis and Systematic Review

Table 1

Characteristics of the included studies and overview of corticosteroid injection related to IA and SA injection for adhesive capsulitis.

StudyStudy designPatients analysed (n)Corticosteroid mixtureDuration of symptomsFollow-up

Sun et al. [21]RCTTotal = 50
IA (24)/SA
(26)
A single injection: 1 mL of 40 mg/mL triamcinolone +2 mL 2% lidocaineIA (15.2 ± 5.0) vs. SA (15.1 ± 4.8) weeks0 (baseline), 4, 8, and 12 weeks after injection

Goyal et al. [20]Quasi-RCTTotal = 70
IA (35)/SA
(35)
40 mg of methylprednisolone acetateIA (15.6 ± 4.9) vs. SA (14.2 ± 4.4) weeksBefore injection, 3, 6 and 12 weeks and 6 months

Khallaf et al. [22]RCTTotal = 40
IA (20)/SA
(20)
A single injection: 1 ml 40 mg methylprednisolone acetate +1 mL 2% lidocaineUnclearBefore injection, 12 weeks after injection

Cho et al. [2]RCTTotal = 73
IA (36)/SA
(37)
A single injection: 1 ml 40 mg triamcinolone acetonide +4 mL 1% lidocaineIA (21.2 ± 14.6) vs. SA (17.4 ± 14.0) weeksBefore injection, 3, 6 and 12 weeks after injection

Yoon et al. [19]RCTTotal = 58
IA (29)/SA
(29)
A single injection: 1 ml 40 mg triamcinolone acetonide +4 mL 2% lidocaine +5 mL normal salineIA (9 ± 6) vs. SA (9 ± 5) monthsBefore treatment and 1 month, 3 months, and 6 months

Ghorai et al. [18]RCTTotal = 51
IA (25)/SA
(26)
A single injection: 1 ml 40 mg depotmethyl prednisolone +1 mL 2% lignocaineUnclearBefore injection, 3, 6 weeks after injection

Shin and Lee [17]RCTTotal = 83
IA (42)/SA
(41)
A single injection: 1 ml 40 mg triamcinolone acetonide +4 mL 2% lidocaineIA (7.4 ± 3.4) vs. SA (7.7 ± 3.3) monthsBefore treatment and at 2, 4, 8, 16, and 24 weeks

Oh et al. [16]RCTTotal = 58
IA (31)/SA
(27)
A single injection: 1 ml 40 mg triamcinolone +4 mL 2% lidocaine +4 mL salineIA (6.2 ± 3.6) vs. SA (6.9 ± 3.4) monthsPreinjection and 3, 6, and 12 weeks after injection

Rizk et al. [15]RCTTotal = 29
IA (15)/SA
(14)
Three injections in the same location at intervals of one week: 1 mL 40 mg/mL methylprednisolone +2 mL of 1% lidocaineMean 13.2 (range 8–18) weeksWeekly for 11 weeks and 15 weeks and six months