Dihydroartemisinin Protects against Dextran Sulfate Sodium-Induced Colitis in Mice through Inhibiting the PI3K/AKT and NF-κB Signaling Pathways

Figure 3

Dihydroartemisinin inhibits production of proinflammatory cytokines in the colon. (a–c) mRNA levels of TNF-α, IL-6, and IL-1β in colonic homogenates determined by qRT-PCR. N = 4 in each group. (d–f) Protein levels of TNF-α, IL-6, and IL-1β in colonic homogenates determined by ELISA. N = 5 in each group. (g–i): Serum concentrations of TNF-α, IL-6, and IL-1β determined by ELISA. N = 6 in each group. vs. control group. vs. DSS group.

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