Toxicity Evaluation of Anacardium occidentale, the Potential Aphrodisiac Herb
Table 12
Values of hematological parameters of female rat orally administered with the leaf extract of A. occidentale for 90 days. Values were as mean±SEM (N=15/group).
Hematological parameters
Reference values
Vehicle
AO 20 mg/kgBW
AO 100 mg/kgBW
AO 500 mg/kgBW
WBC (×103 ells/mm3)
1.98-11.06
5.02±0.41
4.07±0.33
4.03±0.37
2.91±0.25
RBC (×106 cells/mm3)
7.62-9.99
7.77±0.70
8.23±0.20
8.17±0.14
9.17±0.23
Hemoglobin (g/dL)
13.60-17.40
13.35±1.12
14.92±0.31
14.68±0.29
16.11±0.33
Hematocrit (%)
38.50-52.00
42.70±2.73
45.78±0.95
45.50±1.06
51.04±0.98
MCV (fL)
46.30-56.20
57.96±3.02
55.77±0.95
55.67±0.84
55.89±0.88
MCH (pg)
16.30-19.50
17.50±0.41
18.15±0.15
17.97±0.23
17.61±0.20
MCHC (g/dL)
31.90-38.50
30.73±0.98
32.62±0.30
32.32±0.18
31.59±0.36
Platelet (×103 cells/mm3)
547-1253
857.64±60.92
701.47±34.29
691.31±53.72
583.86±57.11
Neutrophil (%)
9.00-49.30
25.91±2.37
23.89±1.88
21.35±1.73
27.76±2.86
Lymphocyte (%)
44.70-87.10
69.96±2.16
71.63±1.75
73.59±1.68
65.51±2.65
Monocyte (%)
1.00-3.60
3.23±0.56
3.95±0.58
4.08±0.66
5.07±1.01
Eosinophil (%)
0.40-4.00
0.90±0.18
1.53±0.32
0.98±0.09
1.64±0.28
Basophil (%)
0-0.60
0.00±0.00
0.08±0.08
0.00±0.00
0.01±0.01
White blood cell count (WBC), red blood cell count (RBC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and hemoglobin concentration (MCHC). P value<.05 and P value<.001, compared to vehicle treated group.
