Toxicity Evaluation of Anacardium occidentale, the Potential Aphrodisiac Herb
Table 13
Values of clinical chemistry parameters of male rat orally administered with the leaf extract of A. occidentale for 90 days. Values were as mean±SEM (N=15/group).
Blood Chemistry
Reference values
Vehicle
AO 20 mg/kgBW
AO 100 mg/kgBW
AO 500 mg/kgBW
BUN(mg/ dL)
10.7-20
19.91±0.70
18.68±0.79
17.95±0.78
19.37±1.02
Creatinine(ml/ dL)
0.3-0.5
0.50±0.02
0.50±0.03
0.47±0.02
0.45±0.02
Cholesterol(ml/ dL)
37-95
64.60±3.29
66.00±2.81
57.00±2.46
60.33±4.72
Triglyceride(ml/ dL)
27-160
75.92±8.24
48.86±7.79
46.40±3.29
46.20±4.27
ALT(U/L)
19-48
123.67±7.89
142.93±7.43
144.64±2.53
140.14±13.11
AST(U/L)
63-175
49.53±7.89
55.93±5.63
38.40±3.23
45.07±3.07
ALP(U/L)
36-131
66.33±5.14
82.60±7.64
54.07±4.49
62.50±5.27
Total Bilirubin(mg/ dL)
0.04-0.2
0.1±0.001
0.12±0.0145
0.1±0.00
0.1±0.00
Alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) P value<.05, P value<01, andP value<.001, compared to vehicle treated group.
